The Yu Lab
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163. Kai-jiong Xiao, Ling Chu and Jin-Quan Yu "Enantioselective C-H Olefination via Kinetic Resolution"
Angew. Chem. Int. Ed.
Early view.
162. Jian He, Heng Jiang, Ryosuke Takise, Ru-Yi Zhu, Gang Chen, Hui-Xiong Dai, T. G. Murali Dhar, Jun Shi, Hao Zhang, Peter T. W. Cheng and Jin-Quan Yu "Ligand-Promoted Borylation of C(sp3)-H Bonds with Pd(II) Catalysts"
Angew. Chem. Int. Ed.
Early view.
161. Ling Chu, Ming Shang, Keita Tanaka, Qinghao Chen, Natalya Pissarnitski, Eric Streckfuss, and Jin-Quan Yu "Remote Meta-C-H Activation Using a Pyridine-Based Template: Achieving Site-Selectivity via the Recognition of Distance and Geometry"
ACS Cent. Sci.
& Highlighted on
ACS Central Science
160. Jillian E. Spangler, Yoshihisa Kobayashi, Pritha Verma, Dong-Hui Wang and Jin-Quan Yu "alpha-Arylation of Saturated Azacycles and N-Methylamines via Palladium(II)-catalyzed C(sp3)-H Coupling"
J. Am. Chem. Soc.
137, 11876.
159. Peng-Xiang Shen, Xiao-Chen Wang, Peng Wang, Ru-Yi Zhu and Jin-Quan Yu "Ligand-Enabled Meta-C-H Alkylation and Arylation Using A Modified Norbornene"
J. Am. Chem. Soc.
137, 11574.
158. Shang-Zheng Sun, Ming Shang, Hong-Li Wang, Hai-Xia Lin, Hui-Xiong Dai and Jin-Quan Yu "Cu(II)-mediated C(sp2)-H Hydroxylation"
J. Org. Chem.
157. Julong Jiang, Jin-Quan Yu and Keiji Morokuma "Mechanism and Stereoselectivity of Directed C(sp3)-H Activation and Arylation Catalyzed by Pd(II) with Pyridine Ligand and Trifluoroacetate: A Computational Study"
ACS Catal.
156. Guolin Cheng, Tuanjie Li and Jin-Quan Yu "Practical Pd(II)-catalyzed C-H Alkylation with Epoxides: One-step Syntheses of 3,4-Dihydroisocoumarins"
J. Am. Chem. Soc.
137, 10950.
155. Hui Xu, Ming Shang, Hui-Xiong Dai and Jin-Quan Yu "Ligand-Controlled para-Selective C-H Arylation of Mono-substituted Arenes"
Org. Lett.
154. Navid Dastbaravardeh, Tetsuya Toba, Marcus Farmer and Jin-Quan Yu "Mono-Selective ortho-C-H Functionalizations of Mandelic Acid and alpha-Phenylglycine"
J. Am. Chem. Soc.
137, 9877.
153. Brandon E. Haines, Xiao-Chen Wang, Jin-Quan Yu and Djamaladdin G. Musaev "Mechanistic Details of the Pd(II)-Catalyzed C-H Iodination by Iodine Molecule: Oxidative Addition vs Electrophilic Cleavage"
J. Am. Chem. Soc.
137, 9022.
152. Brian N. Laforteza, Kelvin S. L. Chan and Jin-Quan Yu "Enantioselective ortho-C-H Cross-Coupling of Diarylmethylamines with Organoborons"
Angew. Chem. Int. Ed.
54, 11143.
151. Ru-Yi Zhu, Keita Tanaka, Gen-Cheng Li, Jian He, Hai-Yan Fu, Su-Hua Li and Jin-Quan Yu "Ligand-Enabled Stereoselective b-C(sp3)-H Fluorination: Synthesis of Unnatural Enantiopure anti-b-Fluoro-a-amino Acids"
J. Am. Chem. Soc.
137, 7067.
150. Gui-Juan Cheng, Ping Chen, Tian-Yu Sun, Xinhao Zhang, Jin-Quan Yu and Yun-Dong Wu "A Combined IM-MS/DFT Study on Pd(MPAA)-Catalyzed Enantioselective C-H Activation: Relay of Chirality through a Rigid Framework"
Chem. Eur. J.
21, 11180.
149. Tao Liu, Tian-Sheng Mei and Jin-Quan Yu "gamma, delta, epsilon-C(sp3)-H Functionalization through A Directed Radical H-Abstraction"
J. Am. Chem. Soc.
137, 5871.
148. Keary M. Engle, Navid Dastbaravardeh, Peter S. Thuy-Boun, DongHui Wang, Aaron C. Sather and Jin-Quan Yu "Ligand-Accelerated ortho-C-H Olefination of Phenylacetic Acids"
Org. Synth.
147. Jian He, Toshihiko Shigenari and Jin-Quan Yu "Palladium(0)/PAr3-Catalyzed Intermolecular Amination of C(sp3)-H Bonds: Synthesis of b-Amino Acids"
Angew. Chem. Int. Ed.
146. Jian He, Ryosuke Takise, Haiyan Fu, Jin-Quan Yu "Ligand-Enabled Cross-Coupling of C(sp3)-H Bonds with Arylsilanes"
J. Am. Chem. Soc.
137, 4618.
145. Gang Li, Li Wan, Guofu Zhang, Dasheng Leow, Jillian Spangler and Jin-Quan Yu "Pd(II)-Catalyzed C-H Functionalizations Directed by Distal Weakly Coordinating Functional Groups"
J. Am. Chem. Soc.
137, 4391.
144. Xiao-Chen Wang, Wei Gong, Li-Zhen Fang, Ru-Yi Zhu, Suhua Li, Keary M. Engle and Jin-Quan Yu "Ligand-enabled meta-C-H activation using a transient mediator"
143. Gang Chen, Toshihiko Shigenari, Pankaj Jain, Zhipeng Zhang, Zhong Jin, Jian He, Suhua Li, Claudio Mapelli, Michael M. Miller, Michael A. Poss, Paul M. Scola, Kap-Sun Yeung and Jin-Quan Yu "Ligand-Enabled beta-C-H Arylation of alpha-Amino Acids Using a Simple and Practical Auxiliary"
J. Am. Chem. Soc.
137, 3338.
142. Kelvin S. L. Chan, Hai-Yan Fu and Jin-Quan Yu "Palladium(II)-Catalyzed Highly Enantioselective C-H Arylation of Cyclopropylmethylamines"
J. Am. Chem. Soc.
137, 2042.
141. Yi Lu, Huai-Wei Wang, Jillian E. Spangler, Kai Chen, Pei-Pei Cui, Yue Zhao, Wei-Yin Sun and Jin-Quan Yu "Rh(III)-catalyzed C-H olefination of N-pentafluoroaryl benzamides using air as the sole oxidant"
Chem. Sci.
140. Dajian Zhu, Guoqiang Yang, Jian He, Ling Chu, Gang Chen, Wei Gong, Ke Chen, Martin D. Eastgate and Jin-Quan Yu "Ligand-Promoted ortho-C-H Amination with Pd Catalysts"
Angew. Chem. Int. Ed.
139. Weibo Yang, Shengqing Ye, Dewey Fanning, Timothy Coon, Yvonne Schmidt, Paul Krenitsky, Dean Stamos and Jin-Quan Yu "Orchestrated Triple C-H Activation Reactions Using Two Directing Groups: Rapid Assembly of Complex Pyrazoles"
Angew. Chem. Int. Ed.
138. Youqian Deng and Jin-Quan Yu "Remote meta-C-H Olefination of Phenylacetic Acids Directed by a Versatile U-Shaped Template"
Angew. Chem. Int. Ed.
137. Yue-Jin Liu,Hui Xu, Wei-Jun Kong, Ming Shang, Hui-Xiong Dai and Jin-Quan Yu "Overcoming the limitations of directed C-H functionalizations of heterocycles"
136. Ling Chu, Kai-Jiong Xiao and Jin-Quan Yu "Room-temperature enantioselective C-H iodination via kinetic resolution"
& Featured in
TSRI News & Views
135. Jin-Quan Yu "Directed C-H Activation Reactions of Synthetically Versatile Substrates: A Journey to Practicality"
Adv. Synth. Catal.
356, 1393.
& Commentaries
134. Ming Shang,
Shang-Zheng Sun, Hui-Xiong Dai and Jin-Quan Yu "Cu(OAc)2-Catalyzed Coupling of Aromatic C-H Bonds with Arylboron Reagents"
Org. Lett.
133. Wei Gong, Guofu Zhang, Tao Liu, Ramesh Giri and Jin-Quan Yu "Site-Selective C(sp3)-H Functionalization of Di-, Tri-, and Tetrapeptides at the N-Terminus"
J. Am. Chem. Soc.
136, 16940.
132. Ru-Yi Zhu, Jian He and Jin-Quan Yu "Ligand-Promoted Alkylation of C(sp3)-H and C(sp2)-H Bonds"
J. Am. Chem. Soc.
136, 13194.
131. Ming Shang, Hong-Li Wang, Shang-Zheng Sun, Hui-Xiong Dai and Jin-Quan Yu "Cu(II)-Mediated Ortho C-H Alkynylation of (Hetero)Arenes with Terminal Alkynes"
J. Am. Chem. Soc.
136, 11590.
130. Guoqiang Yang, Petra Lindovska, Dajian Zhu, Justin Kim, Peng Wang, Ri-Yuan Tang, Mohammad Movassaghi and Jin-Quan Yu "Pd(II)-Catalyzed meta-C-H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template"
J. Am. Chem. Soc.
136, 10807.
129. Ming Shang,Shang-Zheng Sun, Hong-Li Wang, Brian N. Laforteza, Hui-Xiong Dai and Jin-Quan Yu "Exceedingly Fast Copper(II)-Promoted ortho C-H Trifluoromethylation of Arenes using TMSCF3"
Angew. Chem. Int. Ed.
53, 10439.
128. Youqian Deng, Wei Gong, Jian He and Jin-Quan Yu "Ligand-Enabled Triple C-H Activation Reactions: One-Pot Synthesis of Diverse 4-Aryl-2-quinolinones from Propionamides"
Angew. Chem. Int. Ed.
127. Kai-Jiong Xiao, David W. Lin, Motofumi Miura, Ru-Yi Zhu, Wei Gong, Masayuki Wasa and Jin-Quan Yu "Palladium(II)-Catalyzed Enantioselective C(sp3)-H Activation Using a Chiral Hydroxamic Acid Ligand"
J. Am. Chem. Soc.
136, 8138.
126. Suhua Li, Gang Chen, Chen-Guo Feng, Wei Gong and Jin-Quan Yu "Ligand-enabled gamma-C-H Olefination and Carbonylation: Construction of beta-Quaternary Carbon Centers"
J. Am. Chem. Soc.
136, 5267.
125. Erik L. Regalado, Marisa C. Kozlowski, John M. Curto, Tobias Ritter, Michael G. Campbell, Anthony R. Mazzotti, Bruce C. Hamper, Christoph er D. Spilling, Michael P. Mannino, Li Wan, Jin-Quan Yu, Jinchu Liu and Christopher J. Welch "Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry"
Org. Biomol. Chem.
124. Jian He, Suhua Li, Youqian Deng, Haiyan Fu, Brian N. Laforteza, Jillian E. Spangler, Anna Homs and Jin-Quan Yu "Ligand-Controlled C(sp3)-H Arylation and Olefination in Syntheses of Unnatural Chiral a-Amino Acids"
343, 1216.
& Highlighted on the Academic Minute
123. Riyuan Tang, Gang Li and Jin-Quan Yu "Conformation-Induced Remote meta-C-H Activation of Amines"
122. Ming Shang, Shang-Zheng Sun, Hui-Xiong Dai and Jin-Quan Yu "Cu(II)-Mediated C-H
Amidation and Amination of Arenes: Exceptional Compatibility with Heterocycles"
J. Am. Chem. Soc.
136, 3354.
121. Kelvin S. L. Chan, Masayuki Wasa, Ling Chu, Brian N. Laforteza, Masanori Miura and Jin-Quan Yu "Ligand-enabled cross-coupling of C(sp3)-H bonds with arylboron reagents via Pd(II)/Pd(0) catalysis"
Nature Chemistry
120. Gui-Juan Cheng, Yun-Fang Yang, Peng Liu, Ping Chen, Tian-Yu Sun, Gang Li, Xinhao Zhang, K. N. Houk, Jin-Quan Yu and Yun-Dong Wu "Role of N-Acyl Amino Acid Ligands on Pd(II)-Catalyzed Remote C–H Activation of Tethered Arenes"
J. Am. Chem. Soc.
119. Harit U. Vora, Anthony P. Silvestri, Casper J. Engelin and Jin-Quan Yu "Rhodium(II)-Catalyzed Non-Directed Oxidative Alkenylation of Arenes: Arene Loading At One Equivalent"
Angew. Chem. Int. Ed.
118. Yun-Fang Yang, Gui-Juan Cheng, Peng Liu, Dasheng Leow, Tian-Yu Sun, Ping Chen, Xinhao Zhang, Jin-Quan Yu, Yun-Dong Wu and K. N. Houk "Palladium-Catalyzed meta-Selective C-H Bond Activation with a Nitrile-Containing Template: A Computational Study on Mechanism and Origins of Selectivity"
J. Am. Chem. Soc.
117. Sandy Ma, Giorgio Villa, Peter S. Thuy-Boun, Anna Homs and Jin-Quan Yu "Pd-Catalyzed ortho-Selective C-H Deuteration of Arenes: Evidence for Superior Reactivity of Weakly Coordinated Palladacycles"
Angew. Chem. Int. Ed.
116. Li Wan, Navid Dastbaravardeh, Gang Li and Jin-Quan Yu "Cross-Coupling of Remote meta-C-H Bonds Directed by a U-Shaped Template"
J. Am. Chem. Soc.
135, 18056.
115. Ling Chu, Xiao-Chen Wang, Curtis E Moore, Arnold L. Rheingold and Jin-Quan Yu "Pd-catalyzed Enantioselective C-H Iodination: Asymmetric Synthesis of Chiral Diarylmethylamines"
J. Am. Chem. Soc.
135, 16344.
& Highlighted by SynFacts, 2014(10): 0046, DOI: 10.1055/s-
114. Peter S. Thuy-Boun, Giorgio Villa, Devin Dang, Paul F Richardson, Shun Su and Jin-Quan Yu "Ligand-Accelerated ortho-C-H Alkylation of Arylcarboxylic Acids using Alkyl Boron Reagents"
J. Am. Chem. Soc.
135, 17508.
113. Ming Shang, Shao-Hang Zeng, Shang-Zheng Sun, Hui-Xiong Dai and Jin-Quan Yu "Ru(II)-Catalyzed ortho-C-H Amination of Arenes and Heteroarenes at Room Temperature"
Org. Lett.
112. Masanori Miura, Chen-Guo Feng, Sandy Ma, and Jin-Quan Yu "Pd(II)-Catalyzed Ortho-Trifluoromethylation of Benzylamines"
Org. Lett.
111. Travis M. Figg, Masayuki Wasa, Jin-Quan Yu and Djamaladdin G. Musaev "Understanding the Reactivity of Pd0/PR3-Catalyzed Intermolecular C(sp3)-H Bond Arylation"
J. Am. Chem. Soc.
135, 14206.
110. Xiao-Chen Wang, Yi Hu, Samuel Bonacorsi, Yang Hong, Richard Burrell, and Jin-Quan Yu "Pd(II)-Catalyzed C-H Iodination Using Molecular I2 as the Sole Oxidant"
J. Am. Chem. Soc.
135, 10326.
& Highlighted on CE&N news
& Highlighted on JACS
109. Chen-Guo Feng, Mengchun Ye, Kai-Jiong Xiao, Suhua Li and Jin-Quan Yu "Pd(II)-Catalyzed Phosphorylation of Aryl C-H Bonds"
J. Am. Chem. Soc.
135, 9322.
108. Tian-Sheng Mei, Dasheng Leow, Han Xiao, Brian N. Laforteza, and Jin-Quan Yu "Synthesis of Indolines via Pd(II)-Catalyzed Amination of C-H Bonds Using PhI(OAc)2 as the Bystanding Oxidant"
Org. Lett.
107. Brandon R. Rosen, Leah R. Simke, Peter S. Thuy-Boun, Darryl D. Dixon, Jin-Quan Yu and Phil S. Baran "C-H Functionalization Logic Enables Synthesis of (+)-Hongoquercin A and Related Compounds"
Angew. Chem., Int. Ed.
& Selected as a "VIP Paper".
106. Keary M. Engle and Jin-Quan Yu "Developing Ligands for Palladium(II)-Catalyzed C-H Functionalization: Intimate Dialogue between Ligand and Substrate"
J. Org. Chem.
& Invited Perspective
105. Hui-Xiong Dai, Gang Li, Xing-Guo Zhang, Antonia F. Stepan, and Jin-Quan Yu "Pd(II)-Catalyzed ortho- or meta-C-H Olefination of Phenol Derivatives"
J. Am. Chem. Soc.
135, 7567.
104. Hengbin Wang , Gang Li , Keary M Engle , Jin-Quan Yu , and Huw Madoc Lynn Davies "Sequential C-H Functionalization Reactions for the Enantioselective Synthesis of Highly Functionalized 2,3-Dihydrofurans"
J. Am. Chem. Soc.
135, 6774.
103. Mengchun Ye, Andrew Edmunds, James Morris, David Sale, Yejia Zhang and Jin-Quan Yu "A Robust Protocol for Pd(II)-catalyzed C-3 Arylation of (1H)Indazoles and Pyrazoles: Total Synthesis of Nigellidine Hydrobromide"
Chem. Sci.
102. Jian He, Masayuki Wasa, Kelvin S. L. Chan, and Jin-Quan Yu "Palladium(0)-Catalyzed Alkynylation of C(sp3)-H Bonds"
J. Am. Chem. Soc.
135, 3387.
101. Xiu-Fen Cheng, Yan Li, Yi-Ming Su, Feng Yin, Jian-Yong Wang, Jie Sheng, Harit U. Vora, Xi-Sheng Wang, and Jin-Quan Yu "Pd(II)-Catalyzed Enantioselective C-H Activation/C-O Bond Formation: Synthesis of Chiral Benzofuranones"
J. Am. Chem. Soc.
135, 1236.
100. Tian-Sheng Mei, Lei Kou, Sandy Ma, Keary M. Engle, Jin-Quan Yu "Heterocycle Formation via Palladium-Catalyzed C-H Functionalization"
99. Gang Li, Dasheng Leow, Li Wan and Jin-Quan Yu "Ether-Directed ortho-C-H Olefination with a Palladium(II)/Monoprotected Amino Acid Catalyst"
Angew. Chem., Int. Ed.
98. Wasa, M.; Chan, K. S. L.; Zhang, X.-G.; He, J.; Miura, M.; Yu, J. -Q. "Ligand-Enabled Methylene C(sp3)-H Bond Activation with a Pd(II) Catalyst."
J. Am. Chem. Soc.
134, 18570.
97. Giri, R.; Lan, Y.; Liu, P.; Houk, K. N.; Yu, J.-Q. "Understanding Reactivity and Stereoselectivity in Palladium-Catalyzed Diastereoselective sp3 C-H Bond Activation: Intermediate Characterization and Computational Studies."
J. Am. Chem. Soc.
134, 14118.
96. Zhang, X.-G.; Dai, H.-X.; Wasa, M.; Yu, J.-Q. "Pd(II)-Catalyzed ortho-Trifluoromethylation of Arenes and Insights into Coordination Mode of Acidic Amide Directing Groups."
J. Am. Chem. Soc.
134, 11948.
95. Leow, D.; Li, G.; Mei, T.-S.; Yu, J.-Q. "Activation of Remote meta-C-H Bond Assisted by an End-on Template."
94. Baxter, R. D.; Sale, D.; Engle, K. M.; Yu, J.-Q.; Blackmond, D. G. "Mechanistic Rationalization of Unusual Kinetics in Pd-Catalyzed C-H Olefination."
J. Am. Chem. Soc.
134, 4600.
93. Dai, H.-X.; Yu, J.-Q. "Pd-Catalyzed Oxidative ortho-C-H Borylation of Arenes."
J. Am. Chem. Soc.
92. Engle, K. M.; Mei, T.-S.; Wasa, M.; Yu, J.-Q. "Weak Coordination as Powerful Means for Developing Broadly Useful C-H Functionalization Reactions."
Acc. Chem. Res.
91. Musaev, D. G.; Kaledinm, A. L.; Shi, B. -F.; Yu, J.-Q. "Key Mechanistic Features of Enantioselective C-H Bond Activation Reactions Catalyzed by [(Chiral Mono-N-Protected Amino Acid)-Pd(II)] Complexes."
J. Am. Chem. Soc.
134, 1690.
90. Wasa, M.; Engle, K. M.; Lin, D. W.; Yoo, E. J.; Yu, J.-Q. "Pd(II)-Catalyzed Enantioselective C-H Activation of Cyclopropanes."
J. Am. Chem. Soc.
133, 19598.
89. Ye, M.; Gao, G.-L.; Edmunds, A. J. F.; Worthington, P. A.; Morris, J. A.; Yu, J.-Q. "Ligand-Promoted C-3-Selective Arylation of Pyridines with Pd Catalysts: Gram-Scale Synthesis of (+/-) Preclamol."
J. Am. Chem. Soc.
133, 19090.
88. Liu, L.; Wu, H.-C.; Yu, J.-Q. "Improved Syntheses of Phosphine Ligands by Direct Coupling of Diarylbromophosphine with Organometallic Reagents."
Chem. Eur. J.
17, 10828.
87. Engle, K. M.; Thuy-Boun, P. S.; Dang, M.; Yu J.-Q. "Ligand-Accelerated Cross-Coupling of C(sp2)-H Bonds with Arylboron Reagents."
J. Am. Chem. Soc.
133, 18183.
86. Wasa M.; Chan, K. S. L; Yu J.-Q. "Pd(II)-Catalyzed Cross-Coupling of C(sp2)-H Bonds and Aryl-, Alkyl-, and Vinyl-Boron Reagents via Pd(II)/Pd(0) Catalysis."
Chem. Lett.
& Paper in celebration of the 2010 Nobel Prize in Chemistry.
85. Wang, X.; Leow D.; Yu, J.-Q. "Pd(II)-Catalyzed para-Selective C-H Arylation of Monosubstituted Arenes."
J. Am. Chem. Soc.
133, 13864.
& The fourth most read JACS article in August 2011.
84. Chan, K. S. L; Wasa M.; Wang X.; Yu J.-Q. "Palladium(II)-Catalyzed Selective Monofluorination of Benzoic Acids Using a Practical Auxiliary: A Weak-Coordination Approach."
Angew. Chem. Int. Ed.
83. Yoo, E. J.; Ma, S.; Mei, T.-S.; Chan, K. S. L.; Yu, J.-Q. "Pd-Catalyzed Intermolecular C-H Amination with Alkylamines."
J. Am. Chem. Soc.
133, 7652.
& The fourth most read JACS article in July 2011.
82. Ye, M.; Gao, G.-L.; Yu, J.-Q. "Ligand-Promoted C-3 Selective C-H Olefination of Pyridines with Pd Catalysts."
J. Am. Chem. Soc.
133, 6964.
& The third most read JACS article in April 2011.
81. Dai, H.-X.; Stepan, A. F.; Plummer, M. S.; Zhang, Y.-H.; Yu, J.-Q. "Divergent C-H Functionalizations Directed by Sufonamide Pharmacophores: Late-Stage Diversification as a Tool for Drug Discovery."
J. Am. Chem. Soc.
133, 7222.
& One of the Top 10 most read JACS articles in April 2011.
80. Wang, D.-H.; Yu, J.-Q. "Highly Convergent Total Synthesis of (+)-Lithospermic Acid via a Late-Stage Intermolecular C-H Olefination."
J. Am. Chem. Soc.
& One of the Top 20 most read JACS articles in March 2011. & Highlighted by SynFacts, 2011(7): , DOI: 10.1055/s-
79. Lu, Y.; Leow, D.; Wang, X.; Engle, K. M.; Yu, J.-Q. "Hydroxyl-Directed C-H Carbonylation Enabled by Mono-N-Protected Amino Acid Ligands: An Expedient Route to 1-Isochromanones."
Chem. Sci.
& Highlighted on the Chemical Science blog & The second most-read Chem. Sci. article in March 2011.
78. Davies, H. M. L.; Du Bois, J.; Yu, J.-Q. "C-H Functionalization in Organic Synthesis"
Chem. Soc. Rev.
77. Engle, K. M.; Mei, T.-S., Wang, X.; Yu, J.-Q. "Bystanding F+ Oxidants Enable Selective Reductive Elimination From High-Valent Metal Centers in Catalysis."
Angew. Chem. Int. Ed.
76. Wasa, M.; Engle, K. M.; Yu, J.-Q. "Cross-coupling of C(sp3)-H Bonds with Organometallic Reagents via Pd(II)/Pd(0) Catalysis."
Isr. J. Chem.
& An invited article for the "Metal-Catalyzed Cross-Coupling Reactions" special issue honoring the 2010 Nobel Prize winners. & Selected for the front cover.
75. Huang, Y.Q.; Liu, G.-X.; Zhou, X.-Y.; Okamura, T.-a.; Su, J.; Fan, J.; Sun, W.-Y.; Yu, J. J.-Q.; Ueyama, N. "Syntheses, Crystal Structures and Properties of Silver(I) and Copper(II) Complexes with an Oxazoline-Containing Tetradentate Ligand."
New. J. Chem.
74. Yoo, E. J.; Wasa, M.; Yu, J.-Q. "Pd(II)-Catalyzed Carbonylation of sp3 C-H Bonds: A New Entry to 1,4-Dicarbonyl Compounds."
J. Am. Chem. Soc.
132, 17378.
& One of the Top 20 most read JACS articles in November 2010. & Featured in SynForm
73. Engle, K. M.; Wang, D.-H.; Yu, J.-Q. "Ligand-Accelerated C-H Olefination Reactions: Evidence for a Switch of Mechanism."
J. Am. Chem. Soc.
132, 14137.
& One of the Top 20 most read JACS articles in September 2010.
72. Wang, X. Lu, Y.; Dai, H.-D; Yu, J.-Q. "Pd(II)-Catalyzed Hydroxy-Directed C-H Activation/C-O Cyclization: Expedient Construction of Dihydrobenzofurans."
J. Am. Chem. Soc.
132 12203.
& One of the Top 10 most read JACS articles in August 2010. & Featured in SynFacts, 2010(11): , DOI: 10.1055/s-
71. Engle, K. M.; Wang, D.-H.; Yu, J.-Q. "Constructing Multiply Substituted Arenes Using Sequential Pd(II)-Catalyzed C-H Olefination."
Angew. Chem. Int. Ed.
70. Mei, T.-S.; Wang, D.-H.; Yu, J.-Q. "Expedient Drug Synthesis and Diversification via ortho-C-H Iodination Using Recyclable PdI2 as the Precatalyst."
Org. Lett.
& One of the Top 20 most read Org. Lett. articles in June 2010. & Featured in SynFacts, 2010(10): , DOI: 10.1055/s-
69. Huang, Y.-Q.; Sheng, Z.-L.; Zhou, X.-Y.; Okamura, T.-a.; Su, J.; Fan, J.; Sun, W.-Y.; Yu, J. J.-Q.; Ueyama, N. "Metal-Organic Frameworks with Oxazoline-Containing Tripodal Liand: Structure Changes via Reaction Medium and Metal-to-Ligand Ratio."
CrystEngComm.
68. Vickers, C.; Mei, T.-S.; Yu, J.-Q. "Pd(II)-Catalyzed ortho-C-H Acetoxylation of Phenylalanine and Ephedrine Derivatives with MeCOOOt-Bu/Ac2O."
Org. Lett.
& One of the Top 10 most read Org. Lett. articles in May 2010.
67. Lu, Y.; Wang, D.-H.; Engle, K. M.; Yu, J-.Q. "Pd(II)-Catalyzed Hydroxyl-Directed C-H Olefination Enabled by Monoprotected Amino Acid Ligands."
J. Am. Chem. Soc.
132, 5916.
& One of the Top 10 most read JACS articles in April 2010.& Featured in SynFacts, 2010(7): , DOI: 10.1055/s-
66. Wasa, M.; Engle, K. M.; Yu, J-.Q. "Pd(II)-Catalyzed Olefination of sp3 C-H Bonds."
J. Am. Chem. Soc.
132, 3680.
& One of the Top 20 most read JACS articles in March 2010. & Featured in SynFacts
65. Wang, X.; Truesdale, L.; Yu, J-.Q. "Pd(II)-Catalyzed ortho-Trifluoromethylation of Arenes Using TFA as a Promoter."
J. Am. Chem. Soc.
132, 3648.
& One of the Top 20 most read JACS articles in February 2010.
64. Wasa, M.; Yu, J-.Q. "Amide-Directed Arylation of sp3 C-H Bonds using Pd(II) and Pd(0) Catalysts."
Tetrahedron
& In honor of Professor Brian Stoltz on his being awarded Tetrahedron Young Investigator Award. & Featured in SynFacts, 2010(9): , DOI: 10.1055/s-
63. Shi, B.-F.; Zhang, Y.-H.; Lam, J. K.; Wang, D.-H.; Yu, J-.Q. "Pd(II)-Catalyzed Enantioselective C-H Olefination of Diphenylacetic Acids."
J. Am. Chem. Soc.
& One of the Top 20 most read JACS articles in December 2009. & Highlighted in Angew. Chem. Int. Ed.
62. Giri, R.; Lam, J. K.; Yu, J-.Q. "Synthetic Applications of Pd(II)-Catalyzed C-H Carboxylation and Mechanistic Insights: Expedient Routes to Anthranilic Acids, Oxazolinones and Quinazolinones."
J. Am. Chem. Soc
& One of the Top 20 most read JACS articles in December 2009.
61. Wasa, M.; Worrell, B. T.; Yu, J.-Q. "Pd(0)/PR3-Catalyzed Arylation of Nicotinic Acid and Isonicotinic Acid Derivatives"
Angew. Chem. Int. Ed.
& Selected as a "Hot Paper." & One of the 10 most accessed Angew. Chem. Int. Ed. articles in January 2010.
60. Wang, D.-H.; Engle, K. M.; Shi, B.-F.; Yu, J.-Q. "Ligand-Enabled Reactivity and Selectivity in a Synthetically Versatile Aryl C-H Olefination"
& Selected as a Science Express paper. & Featured in C&EN News, Science & Technology, Concentrates.
& Featured in RSC's Chemistry World.
& Featured in TSRI News & Views.
& Featured in Science Daily.
& Highlighted in Angew. Chem. Int. Ed.
59. Zhang, Y.-H.; Yu, J.-Q. "Pd(II)-Catalyzed Hydroxylation of Arenes Using 1 atm O2 or Air"
J. Am. Chem. Soc.
131, 14654.
& Featured in C&EN News, Science & Technology, Concentrates .
& One of the Top 20 most read JACS articles in November 2009. & Featured in SynFacts, 2010(2): , DOI: 10.1055/s-
& Featured online at the Organic Chemistry Portal
58. Giri, R.; Shi, B.-F.; Engle, K. M.; Maugel, N.; Yu, J.-Q. "Transition Metal-Catalyzed C-H Activation Reactions: Diastereoselectivity and Enantioselectivity"
Chem. Soc. Rev.
& Part of the "Rapid Formation of Molecular Complexity in Organic Synthesis" Issue
& One of the Top 10 most read Chem. Soc. Rec. articles for three consecutive months 11/09-01/10.
57. Mei, T.-S.; Wang, X.; Yu, J.-Q. "Pd(II)-catalyzed Amination of C-H Bonds Using Single-electron or Two-electron Oxidants"
J. Am. Chem. Soc.
131, 10806.
& Featured in SynFacts, 2009(10): , DOI: 10.1055/s-
& Featured online at the Organic Chemistry Portal
56. Wasa, M.; Engle, K. M.; Yu, J.-Q. "Pd(0)-Catalyzed Intermolecular Arylation of sp3 C-H Bonds"
J. Am. Chem. Soc.
131, 9886.
& Featured in SynFacts, 2009(10): , DOI: 10.1055/s-
55. Wu, H.-C.; Hamid, S. A.; Yu, J.-Q.; Spencer, J. B. "Possible Origin of Electronic Effects in Rh(I)-Catalyzed Enantioselective Hydrogenation"
J. Am. Chem. Soc.
131, 9604.
& In memory of Professor Jonathan B. Spencer.
54. "Zhang, Y.-H.; Shi, B.-F.; Yu, J.-Q." "Pd(II)-Catalyzed ortho-Alkylation of Benzoic Acids with Alkyl Halides"
Angew. Chem. Int. Ed.
& Selected as a "Hot Paper.
53. Wang, X.; Mei, T.-S.; Yu, J.-Q. "Versatile Pd(OTf)2-H2O-Catalyzed ortho-Fluorination Using NMP as a Promoter"
J. Am. Chem. Soc.
131, 7520.
& Featured in C&EN News, Science & Technology, Concentrates.
& Featured in SynFacts, 2009(9): , DOI: 10.1055/s-
& One of the Top 20 most read JACS articles in May 2009.
52. Zhang, Y.-H.; Shi, B.-F.; Yu, J.-Q. "Pd(II)-Catalyzed Olefination of Electron-Deficient Arenes Using 2,6-Dialkyl Pyridine Ligands"
J. Am. Chem. Soc.
131, 5072.
& Featured in Science.
& Reported in C&EN News.
& Featured in ChemCatChem.
& Featured in SynFacts, 2009(7): , DOI: 10.1055/s-
& Featured in Angew. Chem. Int. Ed.
51. Chen, X.; Dobereiner, G.; Hao, X.-S.; Giri, R.; Maugel, N.; Yu, J.-Q. "Cu(II)-Mediated Oxidative Dimerization of 2-Phenylpyridine Derivatives"
Tetrahedron
50. Chen, X.; Engle, K. M.; Wang, D.-H.; Yu, J.-Q. "Pd(II)-Catalyzed C-H Activation/C-C Cross-Coupling Reactions: Versatility and Practicality"
Angew. Chem. Int. Ed.
& In memory of Professor Jonathan B. Spencer. & One of the 10 most accessed Angew. Chem. Int. Ed. articles for the year (06/09-05/10).
49. Wang, D.-H.; Mei, T.-S.; Yu, J.-Q. "Versatile Pd(II)-Catalyzed C-H Activation/Aryl鈭扐ryl Coupling of Benzoic and Phenyl Acetic Acids"
J. Am. Chem. Soc.
130, 17676.
& Featured in SynFacts, 2009(4): , DOI: 10.1055/s-.
48. Wasa, M.; Yu, J.-Q. "Synthesis of beta, gamma and delta-Lactams via Pd(II)-Catalyzed C-H Activation Reactions"
J. Am. Chem. Soc.
130, 14058.
& Featured in SynFacts, 2009(4): , DOI: 10.1055/s-.
47. Giri, R.; Yu, J.-Q. "Synthesis of 1,2 and 1,3-dicarboxylic Acids via Pd(II)-Catalyzed Carboxylation of" Aryl and Vinyl C-H Bonds""
J. Am. Chem. Soc.
130, 14082.
& Featured in ChemCatChem.
46. Li, J.-J.; Mei, T.-S.; Yu, J.-Q. "Synthesis of Indolines and Tetrahydroisoquinolines from Arylethylamines via PdII-catalyzed C-H Activation Reactions""
Angew. Chem. Int. Ed.
& Selected as a VIP paper.
45. Mei, T.-S.; Giri, R.; Maugel, N.; Yu, J.-Q. "Pd-catalyzed mono-selective ortho-halogenation of C-H bonds assisted by counter cations: an orthogonal method to directed ortho-lithiation""
Angew. Chem. Int. Ed.
& Featured in Organic Process Research & Development.
(p. 367鈭?68)
44. Shi, B.-F.; Maugel, N.; Zhang, Y.-H.; Yu, J.-Q. "PdII-Catalyzed Enantioselective Activation of sp2 and sp3 C-H Bonds Using mono Protected Amino Acids as Chiral Ligands"
Angew. Chem. Int. Ed.
& Dedicated to Professor E. J. Corey on the occasion of his 80th birthday. & Selected as a "Hot Paper" and featured on the front cover. & Featured in C&EN News, Latest News.
& Featured in Science.
& Highlighted in Angew. Chem. Int. Ed.
43. Wang, D.-H.; Wasa, M.; Giri, R.; Yu, J.-Q. "Pd(II)-Catalyzed Cross-Coupling of sp3 C-H Bonds with sp2 and sp3 Boronic Acids Using Air as the Oxidant"
J. Am. Chem. Soc.
130, 7190.
& Featured in SynForm.
(p. A99鈭扐100)
42. Giri, R.; Maugel, N. L.; Foxman, B. M.; Yu, J.-Q. "Dehydrogenation of inert alkyl groups by Pd(OAc)2: converting a propyl "group into p-allylic complex via a double C-H bond activation""
Organometallics
41. Li, J.-J.; Giri, R.; Yu, J.-Q. "Remote C-H bond functionalization reveals the distance-dependent isotope effects"
Tetrahedron
& In honor of Professor John Hartwig on his being awarded Tetrahedron Young Investigator Award.
40. Giri, R.; Yu, J.-Q "Iodine monoacetate as a C-H functionalization reagent"
The Encyclopedia of Reagents for Organic Synthesis (e-EROS)
39. Huang, Y.-Q.; Shen, Z.-L.; Okamura, T.; Wang, Y.; Wang, X.-F.; Sun, W.-Y.; Yu, J.-Q.; Ueyama, N. "Silver(I) complexes with oxazoline-containing tripodal ligands: structure variation via counter anions and reaction conditions"
Dalton Trans
38. Huang, Y.-Q.; Zhou, X.-Y.; Shen, Z.-L.; Liu, G.-X.; Yu, J.-Q.; Sun, W.-Y. "Synthesis and crystal stryctyre if a novel Ag(I) 1-D coordination polymer with a 2-oxazoolinyl-containing tripodal ligand"
Acta. Chim. Sinica
37. Giri, R.; Maugel, N. L.; Li, J.-J.; Wang, D.-H.; Breazzano, S. P.; Saunders, L. B.; Yu, J.-Q. "Palladium-catalyzed methylation and arylation of sp2 and sp3 C-H bonds in simple carboxylic acids"
J. Am. Chem. Soc
129, 3510.
& Featured in Organic Process Research & Development.
(p. 367鈭?68)
36. Yu, J.-Q.; Giri, R.; Chen, X. "s-Chelation-directed C-H functionalizations using Pd(II) and Cu(II) catalysts: regioselectivity, stereoselectivity and catalytic turnover"
Org. Biomol. Chem
& Featured on the front cover. & One of the Top 5 most cited OBC articles in .
35. Wang, D.-H.; Wu, D.-F.; Yu, J.-Q. "Palladium-Catalyzed Oxidation of Boc-Protected N-Methylamines with IOAc as the Oxidant: A Boc-Directed sp3 C-H Bond Activation"
Org. Lett.
34. Giri R.; Wasa, M.; Brazzano, S. P.; Yu, J.-Q. "Converting gem-Dimethyl Groups into Cyclopropanes via Pd-Catalyzed Sequential C-H Activation and Radical Cyclization"
Org. Lett.
33. Chen, X.; Goodhue, C. E.; Yu, J.-Q. "Palladium-Catalyzed Alkylation of sp2 and sp3 C-H Bonds with Methylboroxine and Alkylboronic Acids: Two Distinct C-H Activation Pathways"
J. Am. Chem. Soc.
128, 12634.
32. Chen, X.; Hao, X.-S.; Goodhue, C. E.; Yu, J.-Q. "Cu(II)-Catalyzed Functionalizations of Aryl C-H Bonds Using O2 as an Oxidant"
J. Am. Chem. Soc.
128, 6790.
31. Chen, X.; Li, J.-J.; Hao, X.-S.; Goodhue, C. E.; Yu, J.-Q "Palladium-Catalyzed Alkylation of Aryl C-H Bonds with sp3 Organotin Reagents Using Benzoquinone&as a Crucial Promoter"
J. Am. Chem. Soc.
30. Giri, R.; Chen, X.; Hao, X.-S.; Li, J.-J.; Liang, J.; Fan, Z.-P.; Yu, J.-Q. "Catalytic and Stereoselective Iodination of Prochiral C-H Bonds"
Tetrahedron: Asymmetry.
& Invited contribution for a special issue on asymmetric oxidation.
29. Giri, R.; Liang, J.; Lei, J.-G.; Li, J- J.; Wang, D.-H.; Chen, X.; Naggar, I. C.; Guo, C.; Foxman, B. M.; Yu, J.-Q. "Pd-Catalyzed Stereoselective Oxidation of Methyl Groups by Inexpensive Oxidants under Mild Conditions: A Dual Role for Carboxylic Anhydrides in Catalytic C-H Bond Oxidation"
Angew. Chem. Int. Ed.
28. Giri, R.; Chen, X.; Yu, J.-Q. "Palladium-Catalyzed Asymmetric Iodination of Unactivated C-H Bonds under Mild Conditions"
Angew. Chem. Int. Ed.
Graduate student and post-doctoral publications:
27. Wu, H. C.; Yu, J. Q.; Spencer, J. B. "Stereospecific Deoxygenation of Phosphine Oxides with Retention of Configuration Using Triphenylphosphine as an Oxygen Acceptor."
Org. Lett.
26. Ley, S. V.; Mitchell, C.; Pears, D.; Ramarao, C.; Yu, J. Q., Zhou, W. "Recyclable Polyurea-Microencapsulated Pd(0) Nanoparticles: An Efficient Catalyst for Hydrogenolysis of Epoxides"
Org. Lett.
25. Yu, J. Q.; Zhou, P.; Xiao, S. "Highly Selective Hydration of alpha-Pinene over H-Mordenites Pretreated with Quaternary Ammonium Salts."
Chinese J. Chem. (English)
24. Tan, Y. P.; Khatua, S.; Yu, J. Q.; Jenkins, S. J.; Gaunt, M. J.; Spencer, J. B.; King, D. A. "Catalyst-Induced Changes in a Substituted Aromatic: A Combined Approach via Experiment and Theory."
Surf. Sci.
23. Yu, J. Q.; Wu, H. C.; Corey, E. J. "Pd(OH)2/C-Mediated Selective Oxidation of Silyl Enol Ethers by tert-Butylhydroperoxide, a Useful Method for the Conversion of Ketones to alpha,beta-enones or beta-silyloxy-alpha,beta-enones."
Org. Lett.
22. Wabnitz, T. C.; Yu, J. Q.; Spencer, J. B "Evidence that proton can be the active catalyst in Lewis acid-mediated Hetero-Michael additions."
Chem. Eur. J.
21. Yu, J. Q.; Corey, E. J. "A mild, catalytic and highly selective method for oxidation of a,b-enones to 1,4-enediones."
J. Am. Chem. Soc.
125, 3232.
20. Yu, J. Q.; Wu, H. C.; Ramarao, C.; Spencer, J. B.; Ley, S. V. "Transfer hydrogenation using recyclable polyurea encapsulated palladium: efficient and chemoselective reduction of aryl ketones."
Chem. Commun.
19. T. C.; Yu, J. Q.; Spencer, J. B. "A general, polymer-supported acid catalyzed hetero-Michael addition."
18. Huang, F. L.; Li, Y. Y.; Yu, J. Q.; Spencer, J. B. "Biosynthesis of aminoglycoside antibiotics: cloning, expression and characterization of an aminotransferase involved in the pathway to 2-deoxystreptamine."
Chem. Commun.
17. Yu, J. Q.; Corey, E. J. "Diverse pathways for the palladium(II)-mediated oxidation of olefins by tert-butylhydroperoxide."
Org. Lett.
16. Yu, J. Q.; Gaunt, M. J.; Spencer, J. B. "Convenient preparation of trans-arylalkenes via palladium(II)-catalyzed summarization of cis-arylalkenes."
J. Org. Chem.
15. Gaunt, M. J.; Yu, J. Q.; Spencer,& J. B. "Evidence that availability of allylic hydrogen governs the regioselectivity of Wacker oxidation."
Chem. Commun.
14. Yu, J. Q.; Spencer, J. B. "Convenient syntheses of 2-deoxy-scyllo-inosose and 2-deoxy-scyllo-inosamine: two key intermediates on the biosynthetic pathway to aminoglycoside antibiotics."
Tetrahedron Lett.
13. Wright, J. A; Yu, J. Q.; Spencer, J. B. "Sequential removal of the benzyl-type protecting groups PMB and NAP by oxidative cleavage using CAN and DDQ."
Tetrahedron Lett.
12. Papageorgiou E. A.; Gaunt,& M. J.; Yu, J. Q.; Spencer,& J. B. "Selective hydrogenolysis of novel benzyl carbamate protecting groups."
Org. Lett.
11. Yu, J. Q.; Spencer, J. B. "Evidence for direct hydride delivery from formic acid in transfer hydrogenation."
Chem. Eur. J.
10. Yu, J. Q.; Whitney, P.-S.; Spencer, J. B. "Direct comparison between homogeneous and heterogeneous hydrogenation."
J. Mol. Catal. A-Chem.
9. Gaunt M. J.; Boschetti C. E.; Yu, J. Q.; Spencer, J. B. "Preferential hydrogenolysis of NAP esters provides a new orthogonal protecting group strategy for carboxylic acids."
Tetrahedron Lett.
8. Yu, J. Q.; Spencer, J. B. "New insight into the mechanism of catalytic hydrogenation allows the key intermediate in asymmetric hydrogenation to be predicted."
Tetrahedron
54, 15821.
7. Yu, J. Q.; Spencer, J. B. "Heterogeneous transfer hydrogenation involves pairwise hydrogen transfer from the same position of two molecules of formic acid."
Chem. Commun.
6. Gaunt, M. J.; Yu, J. Q.; Spencer, J. B. "Rational design of& benzyl protecting groups allows sequential deprotection of hydroxyl groups by catalytic hydrogenolysis."
J. Org. Chem.
5. Yu, J. Q.; Spencer, J. B. "Discovery that quinoline and triphenylphosphine alter the electronic properties of hydrogenation catalysts."
Chem. Commun.
4. Yu, J. Q.; Spencer, J. B. "Regioselective hydrometalation of alkenes reveals the amphipolar nature of the Pd-H bond in heterogeneous hydrogenation."
J. Org. Chem.
3. Yu, J. Q.; Spencer, J. B. "First evidence that the mechanism of catalytic hydrogenation with homogeneous palladium and rhodium catalysts is strongly influenced by substrate polarity."
J. Am. Chem. Soc.
119, 5257.
2. Yu, J. Q.; Spencer, J. B. "Stereoselective deoxygenation of myo-inositol monotosylates with lithium triethylborohydride."
J. Org. Chem.
1. Liu, B.; Yu, J. Q.; Xiao, S. "Selective reaction of camphene with phenols catalyzed by mordenite."
J. Org. Chem. (Chinese)}