nanotechnology iop配得上1区吗
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时间：2015-03-29 05:40
小木虫 --- 500万硕博科研人员喜爱的学术科研平台
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感觉Nanotechnology投稿怎么这么随意呢。。。
虽然之前看了很多的文章，说Nanotechnology的投稿比较随意，但是今天自己提交的时候，还是深深的被雷到了。
（1）也没有注册帐户，直接就提交了。
（2）只有1页的信息让我填，好少啊。以前APL要写好多页呢。
（3）最后一步是上传文件，也没有什么提示，上传完了之后，就直接一下子跳到Submission Complete。什么也没说，就完了。。。
（4）随后收到一封邮件，说收到了提交的手稿，然后给了临时的ID，说过几天再给永久的ID，到时候才能查状态。
&&总体来讲，有点不负责任的感觉。。。 不像是个正规的期刊啊。。。
&&请问大家，下面我就等着啦？也没什么事情啊？
&&还有，这个杂志不是说不让推荐人嘛，怎么好像有这个选项，我推荐了几个审稿人，希望能选上啊。。。
什么。2个月没有送审？ 怎么可能？
我还要抓紧时间毕业呢？ 怎么办啊。。。。
我原来是投了APL，被reject，老板非要投Nanotechnology，这个可怎么办啊？。。。。
发了两封催告信了，编辑都不理睬，准备撤稿，以后再也不投这个了
个人觉得这个杂志的编辑还是很负责的，给他们发邮件基本上一两天就能得到答复，态度也还不错。IOP的投稿系统还好吧，我倒是很喜欢这种简洁的投稿流程。
应该还不错吧，从IF上看，但是据说还是不如APL的说
请问in progress 是还在编辑手里吗，有木有送审啊~谢谢了，手里有篇文章就是这个状态~
我也和你一样，出现过同样的问题，快两周了，没有音讯。想请问下，你的文章后来是什么情况
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随时随地聊科研From Wikipedia, the free encyclopedia
For the materials science journal, see .
Nanotechnology ("nanotech") is manipulation of matter on an , , and
scale. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as . A more generalized description of nanotechnology was subsequently established by the , which defines nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 . This definition reflects the fact that
effects are important at this
scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore common to see the plural form "nanotechnologies" as well as "nanoscale technologies" to refer to the broad range of research and applications whose common trait is size. Because of the variety of potential applications (including industrial and military), governments have invested billions of dollars in nanotechnology research. Until 2012, through its National Nanotechnology Initiative, the USA has invested 3.7 billion dollars, the European Union has invested 1.2 billion and Japan 750 million dollars.
Nanotechnology as defined by size is naturally very broad, including fields of science as diverse as , , , , , , etc. The associated research and applications are equally diverse, ranging from extensions of conventional
to completely new approaches based upon , from developing
with dimensions on the nanoscale to .
Scientists currently debate the future . Nanotechnology may be able to create many new materials and devices with a vast range of , such as in , ,
energy production, and consumer products. On the other hand, nanotechnology raises many of the same issues as any new technology, including concerns about the
and environmental impact of nanomaterials, and their potential effects on global economics, as well as speculation about various . These concerns have led to a debate among advocacy groups and governments on whether special
is warranted.
Main article:
The concepts that seeded nanotechnology were first discussed in 1959 by renowned physicist
in his talk , in which he described the possibility of synthesis via direct manipulation of atoms. The term "nano-technology" was first used by
in 1974, though it was not widely known.
Comparison of Nanomaterials Sizes
Inspired by Feynman's concepts,
used the term "nanotechnology" in his 1986 book , which proposed the idea of a nanoscale "assembler" which would be able to build a copy of itself and of other items of arbitrary complexity with atomic control. Also in 1986, Drexler co-founded
(with which he is no longer affiliated) to help increase public awareness and understanding of nanotechnology concepts and implications.
Thus, emergence of nanotechnology as a field in the 1980s occurred through convergence of Drexler's theoretical and public work, which developed and popularized a conceptual framework for nanotechnology, and high-visibility experimental advances that drew additional wide-scale attention to the prospects of atomic control of matter. In the 1980s, two major breakthroughs sparked the growth of nanotechnology in modern era.
First, the invention of the
in 1981 which provided unprecedented visualization of individual atoms and bonds, and was successfully used to manipulate individual atoms in 1989. The microscope's developers
received a
in 1986. Binnig,
and Gerber also invented the analogous
that year.
Buckminsterfullerene C60, also known as the , is a representative member of the
known as . Members of the fullerene family are a major subject of research falling under the nanotechnology umbrella.
were discovered in 1985 by , , and , who together won the 1996 . C60 was not initially describ the term was used regarding subsequent work with related
tubes (called
and sometimes called Bucky tubes) which suggested potential applications for nanoscale electronics and devices.
In the early 2000s, the field garnered increased scientific, political, and commercial attention that led to both controversy and progress. Controversies emerged regarding the definitions and potential implications of nanotechnologies, exemplified by the 's report on nanotechnology. Challenges were raised regarding the feasibility of applications envisioned by advocates of molecular nanotechnology, which culminated in a public debate between Drexler and Smalley in 2001 and 2003.
Meanwhile, commercialization of products based on advancements in nanoscale technologies began emerging. These products are limited to bulk applications of
and do not involve atomic control of matter. Some examples include the
platform for using
as an antibacterial agent, -based transparent sunscreens,
strengthening using silica nanoparticles, and carbon nanotubes for stain-resistant textiles.
Governments moved to promote and
into nanotechnology, such as in the U.S. with the , which formalized a size-based definition of nanotechnology and established funding for research on the nanoscale, and in Europe via the European .
By the mid-2000s new and serious scientific attention began to flourish. Projects emerged to produce nanotechnology roadmaps which center on atomically precise manipulation of matter and discuss existing and projected capabilities, goals, and applications.
Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced. In its original sense, nanotechnology refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products.
(nm) is one billionth, or 10-9, of a meter. By comparison, typical carbon-carbon , or the spacing between these
in a , are in the range 0.12–0.15 nm, and a
double-helix has a diameter around 2 nm. On the other hand, the smallest
life-forms, the bacteria of the genus , are around 200 nm in length. By convention, nanotechnology is taken as the scale range 1 to 100 nm following the definition used by the National Nanotechnology Initiative in the US. The lower limit is set by the size of atoms (hydrogen has the smallest atoms, which are approximately a quarter of a nm diameter) since nanotechnology must build its devices from atoms and molecules. The upper limit is more or less arbitrary but is around the size below which phenomena not observed in larger structures start to become apparent and can be made use of in the nano device. These new phenomena make nanotechnology distinct from devices which are merely miniaturised versions of a such devices are on a larger scale and come under the description of .
To put that scale in another context, the comparative size of a nanometer to a meter is the same as that of a marble to the size of the earth. Or another way of putting it: a nanometer is the amount an average man's beard grows in the time it takes him to raise the razor to his face.
Two main approaches are used in nanotechnology. In the "bottom-up" approach, materials and devices are built from molecular components which
chemically by principles of . In the "top-down" approach, nano-objects are constructed from larger entities without atomic-level control.
Areas of physics such as , ,
have evolved during the last few decades to provide a basic scientific foundation of nanotechnology.
on a clean () surface, as visualized using . The positions of the individual atoms composing the surface are visible.
Main article:
Several phenomena become pronounced as the size of the system decreases. These include
effects, as well as
effects, for example the " size effect" where the electronic properties of solids are altered with great reductions in particle size. This effect does not come into play by going from macro to micro dimensions. However, quantum effects can become significant when the nanometer size range is reached, typically at distances of 100 nanometers or less, the so-called . Additionally, a number of physical (mechanical, electrical, optical, etc.) properties change when compared to macroscopic systems. One example is the increase in surface area to volume ratio altering mechanical, thermal and catalytic properties of materials. Diffusion and reactions at nanoscale, nanostructures materials and nanodevices with fast ion transport are generally referred to nanoionics. Mechanical properties of nanosystems are of interest in the nanomechanics research. The catalytic activity of nanomaterials also opens potential risks in their interaction with .
Materials reduced to the nanoscale can show different properties compared to what they exhibit on a macroscale, enabling unique applications. For instance, opaque substances can become transparent (copper); stable materials can turn combustible (aluminium); insoluble materials may become soluble (gold). A material such as gold, which is chemically inert at normal scales, can serve as a potent chemical
at nanoscales. Much of the fascination with nanotechnology stems from these quantum and surface phenomena that matter exhibits at the nanoscale.
Main article:
has reached the point where it is possible to prepare small molecules to almost any structure. These methods are used today to manufacture a wide variety of useful chemicals such as
or commercial . This ability raises the question of extending this kind of control to the next-larger level, seeking methods to assemble these single molecules into
consisting of many molecules arranged in a well defined manner.
These approaches utilize the concepts of molecular self-assembly and/or
to automatically arrange themselves into some useful conformation through a
approach. The concept of molecular recognition is especially important: molecules can be designed so that a specific configuration or arrangement is favored due to
. The Watson–Crick
rules are a direct result of this, as is the specificity of an
being targeted to a single , or the specific
itself. Thus, two or more components can be designed to be complementary and mutually attractive so that they make a more complex and useful whole.
Such bottom-up approaches should be capable of producing devices in parallel and be much cheaper than top-down methods, but could potentially be overwhelmed as the size and complexity of the desired assembly increases. Most useful structures require complex and thermodynamically unlikely arrangements of atoms. Nevertheless, there are many examples of self-assembly based on molecular recognition in , most notably Watson–Crick basepairing and enzyme-substrate interactions. The challenge for nanotechnology is whether these principles can be used to engineer new constructs in addition to natural ones.
Main article:
Molecular nanotechnology, sometimes called molecular manufacturing, describes engineered nanosystems (nanoscale machines) operating on the molecular scale. Molecular nanotechnology is especially associated with the , a machine that can produce a desired structure or device atom-by-atom using the principles of . Manufacturing in the context of
is not related to, and should be clearly distinguished from, the conventional technologies used to manufacture nanomaterials such as carbon nanotubes and nanoparticles.
When the term "nanotechnology" was independently coined and popularized by
(who at the time was unaware of an
by Norio Taniguchi) it referred to a future manufacturing technology based on
systems. The premise was that molecular scale biological analogies of traditional machine components demonstrated molecular machines were possible: by the countless examples found in biology, it is known that sophisticated,
can be produced.
It is hoped that developments in nanotechnology will make possible their construction by some other means, perhaps using
principles. However, Drexler and other researchers have proposed that advanced nanotechnology, although perhaps initially implemented by biomimetic means, ultimately could be based on mechanical engineering principles, namely, a manufacturing technology based on the mechanical functionality of these components (such as gears, bearings, motors, and structural members) that would enable programmable, positional assembly to atomic specification. The physics and engineering performance of exemplar designs were analyzed in Drexler's book Nanosystems.
In general it is very difficult to assemble devices on the atomic scale, as one has to position atoms on other atoms of comparable size and stickiness. Another view, put forth by Carlo Montemagno, is that future nanosystems will be hybrids of silicon technology and biological molecular machines. Richard Smalley argued that mechanosynthesis are impossible due to the difficulties in mechanically manipulating individual molecules.
This led to an exchange of letters in the
publication
in 2003. Though biology clearly demonstrates that molecular machine systems are possible, non-biological molecular machines are today only in their infancy. Leaders in research on non-biological molecular machines are Dr.
and his colleagues at Lawrence Berkeley Laboratories and UC Berkeley. They have constructed at least three distinct molecular devices whose motion is controlled from the desktop with changing voltage: a nanotube , a molecular actuator, and a nanoelectromechanical relaxation oscillator. See
for more examples.
An experiment indicating that positional molecular assembly is possible was performed by Ho and Lee at
in 1999. They used a scanning tunneling microscope to move an individual carbon monoxide molecule (CO) to an individual iron atom (Fe) sitting on a flat silver crystal, and chemically bound the CO to the Fe by applying a voltage.
Graphical representation of a , useful as a .
is an artificially
nanostructure of the type made in the field of . Each edge of the tetrahedron is a 20 base pair DNA , and each vertex is a three-arm junction.
Rotating view of C60, one kind of fullerene.
This device transfers energy from nano-thin layers of
above them, causing the nanocrystals to emit visible light.
The nanomaterials field includes subfields which develop or study materials having unique properties arising from their nanoscale dimensions.
has given rise to many materials which may be useful in nanotechnology, such as carbon nanotubes and other fullerenes, and various nanoparticles and . Nanomaterials with fast ion transport are related also to nanoionics and nanoelectronics.
Nanoscale materials can also be used f most present commercial applications of nanotechnology are of this flavor.
Progress has been made in using these materials for
Nanoscale materials such as
are sometimes used in
which combats the cost of traditional
solar cells.
Development of applications incorporating semiconductor
to be used in the next generation of products, such as display technology, lighting, solar cells an see .
Recent application of
include a range of
applications, such as , , and .
These seek to arrange smaller components into more complex assemblies.
DNA nanotechnology utilizes the specificity of Watson–Crick basepairing to construct well-defined structures out of DNA and other .
Approaches from the field of "classical" chemical synthesis (Inorganic and ) also aim at designing molecules with well-defined shape (e.g. ).
More generally, molecular self-assembly seeks to use concepts of supramolecular chemistry, and molecular recognition in particular, to cause single-molecule components to automatically arrange themselves into some useful conformation.
tips can be used as a nanoscale "write head" to deposit a chemical upon a surface in a desired pattern in a process called . This technique fits into the larger subfield of .
These seek to create smaller devices by using larger ones to direct their assembly.
Many technologies that descended from conventional
for fabricating
are now capable of creating features smaller than 100 nm, falling under the definition of nanotechnology. -based hard drives already on the market fit this description, as do
(ALD) techniques.
received the Nobel Prize in Physics in 2007 for their discovery of Giant magnetoresistance and contributions to the field of spintronics.
Solid-state techniques can also be used to create devices known as
or NEMS, which are related to
can directly remove material, or even deposit material when suitable precursor gasses are applied at the same time. For example, this technique is used routinely to create sub-100 nm sections of material for analysis in .
Atomic force microscope tips can be used as a nanoscale "write head" to deposit a resist, which is then followed by an etching process to remove material in a top-down method.
These seek to develop components of a desired functionality without regard to how they might be assembled.
for the synthesis of anisotropic superparamagnetic materials such as recently presented .
seeks to develop molecules with useful electronic properties. These could then be used as single-molecule components in a nanoelectronic device. For an example see rotaxane.
Synthetic chemical methods can also be used to create , such as in a so-called .
seeks to apply biological methods and systems found in nature, to the study and design of engineering systems and modern technology.
is one example of the systems studied.
is the use of
for applications in nanotechnology, including use of viruses and lipid assemblies.
is a potential bulk-scale application.
These subfields seek to
what inventions nanotechnology might yield, or attempt to propose an agenda along which inquiry might progress. These often take a big-picture view of nanotechnology, with more emphasis on its societal implications than the details of how such inventions could actually be created.
Molecular nanotechnology is a proposed approach which involves manipulating single molecules in finely controlled, deterministic ways. This is more theoretical than the other subfields, and many of its proposed techniques are beyond current capabilities.
centers on self-sufficient machines of some functionality operating at the nanoscale. There are hopes for applying nanorobots in medicine, but it may not be easy to do such a thing because of several drawbacks of such devices. Nevertheless, progress on innovative materials and methodologies has been demonstrated with some patents granted about new nanomanufacturing devices for future commercial applications, which also progressively helps in the development towards nanorobots with the use of embedded nanobioelectronics concepts.
Productive nanosystems are "systems of nanosystems" which will be complex nanosystems that produce atomically precise parts for other nanosystems, not necessarily using novel nanoscale-emergent properties, but well-understood fundamentals of manufacturing. Because of the discrete (i.e. atomic) nature of matter and the possibility of exponential growth, this stage is seen as the basis of another industrial revolution. , one of the architects of the USA's National Nanotechnology Initiative, has proposed four states of nanotechnology that seem to parallel the technical progress of the Industrial Revolution, progressing from passive nanostructures to active nanodevices to complex
and ultimately to productive nanosystems.
seeks to design materials whose properties can be easily, reversibly and externally controlled though a fusion of
Due to the popularity and media exposure of the term nanotechnology, the words
have been coined in analogy to it, although these are only used rarely and informally.
Nanomaterials can be classified in 0D, 1D, 2D and 3D . The dimensionality play a major role in determining the characteristic of nanomaterials including ,
characteristics. With the decrease in dimensionality, an increase in surface-to-volume ratio is observed. This indicate that smaller dimensional
have higher surface area compared to 3D nanomaterials. Recently,
are extensively investigated for , ,
applications.
setup. A microfabricated
with a sharp tip is deflected by features on a sample surface, much like in a
but on a much smaller scale. A
beam reflects off the backside of the cantilever into a set of , allowing the deflection to be measured and assembled into an image of the surface.
There are several important modern developments. The
(AFM) and the
(STM) are two early versions of scanning probes that launched nanotechnology. There are other types of . Although conceptually similar to the scanning
developed by
in 1961 and the
(SAM) developed by
and coworkers in the 1970s, newer scanning probe microscopes have much higher resolution, since they are not limited by the wavelength of sound or light.
The tip of a scanning probe can also be used to manipulate nanostructures (a process called positional assembly).
methodology may be a promising way to implement these nanomanipulations in automatic mode. However, this is still a slow process because of low scanning velocity of the microscope.
Various techniques of nanolithography such as ,
dip pen nanolithography,
were also developed. Lithography is a top-down fabrication technique where a bulk material is reduced in size to nanoscale pattern.
Another group of nanotechnological techniques include those used for fabrication of
and , those used in semiconductor fabrication such as deep ultraviolet lithography, electron beam lithography, focused ion beam machining, nanoimprint lithography, atomic layer deposition, and molecular vapor deposition, and further including molecular self-assembly techniques such as those employing di-block copolymers. The precursors of these techniques preceded the nanotech era, and are extensions in the development of scientific advancements rather than techniques which were devised with the sole purpose of creating nanotechnology and which were results of nanotechnology research.
The top-down approach anticipates nanodevices that must be built piece by piece in stages, much as manufactured items are made. Scanning probe microscopy is an important technique both for characterization and synthesis of nanomaterials. Atomic force microscopes and scanning tunneling microscopes can be used to look at surfaces and to move atoms around. By designing different tips for these microscopes, they can be used for carving out structures on surfaces and to help guide self-assembling structures. By using, for example, feature-oriented scanning approach, atoms or molecules can be moved around on a surface with scanning probe microscopy techniques. At present, it is expensive and time-consuming for mass production but very suitable for laboratory experimentation.
In contrast, bottom-up techniques build or grow larger structures atom by atom or molecule by molecule. These techniques include chemical synthesis,
and positional assembly.
is one tool suitable for characterisation of self assembled thin films. Another variation of the bottom-up approach is
or MBE. Researchers at
like John R. Arthur. Alfred Y. Cho, and Art C. Gossard developed and implemented MBE as a research tool in the late 1960s and 1970s. Samples made by MBE were key to the discovery of the fractional quantum Hall effect for which the 1998 Nobel Prize in Physics was awarded. MBE allows scientists to lay down atomically precise layers of atoms and, in the process, build up complex structures. Important for research on semiconductors, MBE is also widely used to make samples and devices for the newly emerging field of .
However, new therapeutic products, based on responsive nanomaterials, such as the ultradeformable, stress-sensitive
vesicles, are under development and already approved for human use in some countries.
One of the major applications of nanotechnology is in the area of
with 's being made of small
~10 nm in length. Here is a simulation of such a nanowire.
Nanostructures provide this surface with , which lets
roll down the .
Main article:
As of August 21, 2008, the
estimates that over 800 manufacturer-identified nanotech products are publicly available, with new ones hitting the market at a pace of 3–4 per week. The project lists all of the products in a publicly accessible online database. Most applications are limited to the use of "first generation" passive nanomaterials which includes titanium dioxide in sunscreen, cosmetics, surface coatings, an Carbon allotro silver in food packaging, clothing, disinfectants and
zinc oxide in sunscreens and cosmetics, surface coatings, paints and outdoor and cerium oxide as a fuel catalyst.
Further applications allow
to last longer,
to fly straighter, and even
to become more durable and have a harder surface.
have been infused with nanotechnology so that they will last longer and keep people cool in the summer.
are being infused with silver nanoparticles to heal cuts faster.
may become cheaper, faster, and contain more memory thanks to nanotechnology. Nanotechnology may have the ability to make existing medical applications cheaper and easier to use in places like the 's office and at home. Cars are being manufactured with
so they may need fewer
to operate in the future.
Scientists are now turning to nanotechnology in an attempt to develop diesel engines with cleaner exhaust fumes. Platinum is currently used as the diesel engine
in these engines. The catalyst is what cleans the exhaust fume particles. First a reduction catalyst is employed to take nitrogen atoms from NOx molecules in order to free oxygen. Next the oxidation catalyst oxidizes the hydrocarbons and carbon monoxide to form carbon dioxide and water. Platinum is used in both the reduction and the oxidation catalysts. Using platinum though, is inefficient in that it is expensive and unsustainable. Danish company InnovationsFonden invested DKK 15 million in a search for new catalyst substitutes using nanotechnology. The goal of the project, launched in the autumn of 2014, is to maximize surface area and minimize the amount of material required. Objects tend to minimize
two drops of water, for example, will join to form one drop and decrease surface area. If the catalyst's surface area that is exposed to the exhaust fumes is maximized, efficiency of the catalyst is maximized. The team working on this project aims to create nanoparticles that will not merge. Every time the surface is optimized, material is saved. Thus, creating these nanoparticles will increase the effectiveness of the resulting diesel engine catalyst—in turn leading to cleaner exhaust fumes—and will decrease cost. If successful, the team hopes to reduce platinum use by 25%.
Nanotechnology also has a prominent role in the fast developing field of . When designing scaffolds, researchers attempt to the mimic the nanoscale features of a 's microenvironment to direct its differentiation down a suitable lineage. For example, when creating scaffolds to support the growth of bone, researchers may mimic
Researchers have successfully used -based nanobots capable of carrying out logic functions to achieve targeted drug delivery in cockroaches. It is said that the computational power of these nanobots can be scaled up to that of a .
Main article:
An area of concern is the effect that industrial-scale manufacturing and use of nanomaterials would have on human health and the environment, as suggested by
research. For these reasons, some groups advocate that nanotechnology be regulated by governments. Others counter that overregulation would stifle scientific research and the development of beneficial innovations.
research agencies, such as the
are actively conducting research on potential health effects stemming from exposures to nanoparticles.
Some nanoparticle products may have . Researchers have discovered that
silver nanoparticles used in socks to reduce foot odor are being released in the wash. These particles are then flushed into the waste water stream and may destroy bacteria which are critical components of natural ecosystems, farms, and waste treatment processes.
Public deliberations on
in the US and UK carried out by the Center for Nanotechnology in Society found that participants were more positive about nanotechnologies for energy applications than for health applications, with health applications raising moral and ethical dilemmas such as cost and availability.
Experts, including director of the Woodrow Wilson Center's Project on Emerging Nanotechnologies David Rejeski, have testified that successful commercialization depends on adequate oversight, risk research strategy, and public engagement.
is currently the only city in the United States to reg
in 2008 considered enacting a similar law, but ultimately rejected it. Relevant for both research on and application of nanotechnologies, the
of nanotechnology is contested. Without state , the availability of private insurance for potential damages is seen as necessary to ensure that burdens are not socialised implicitly.
A video on the health and safety implications of nanotechnology
Main articles:
Nanofibers are used in several areas and in different products, in everything from aircraft wings to tennis rackets. Inhaling airborne nanoparticles and nanofibers may lead to a number of , e.g. . Researchers have found that when rats breathed in nanoparticles, the particles settled in the brain and lungs, which led to significant increases in biomarkers for inflammation and stress response and that nanoparticles induce skin aging through oxidative stress in hairless mice.
A two-year study at UCLA's School of Public Health found lab mice consuming nano-titanium dioxide showed DNA and chromosome damage to a degree "linked to all the big killers of man, namely cancer, heart disease, neurological disease and aging".
A major study published more recently in
suggests some forms of carbon nanotubes – a poster child for the "nanotechnology revolution" – could be as harmful as
if inhaled in sufficient quantities.
of the Institute of Occupational Medicine in Edinburgh, Scotland, who contributed to the article on
said "We know that some of them probably have the potential to cause mesothelioma. So those sorts of materials need to be handled very carefully." In the absence of specific regulation forthcoming from governments, Paull and Lyons (2008) have called for an exclusion of engineered nanoparticles in food. A newspaper article reports that workers in a paint factory developed serious lung disease and nanoparticles were found in their lungs.
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Calls for tighter regulation of nanotechnology have occurred alongside a growing debate related to the human health and safety risks of nanotechnology. There is significant debate about who is responsible for the regulation of nanotechnology. Some regulatory agencies currently cover some nanotechnology products and processes (to varying degrees) – by "bolting on" nanotechnology to existing regulations – there are clear gaps in these regimes. Davies (2008) has proposed a regulatory road map describing steps to deal with these shortcomings.
Stakeholders concerned by the lack of a regulatory framework to assess and control risks associated with the release of nanoparticles and nanotubes have drawn parallels with
("mad cow" disease), , genetically modified food, nuclear energy, reproductive technologies, biotechnology, and . Dr. Andrew Maynard, chief science advisor to the Woodrow Wilson Center's Project on Emerging Nanotechnologies, concludes that there is insufficient funding for human health and safety research, and as a result there is currently limited understanding of the human health and safety risks associated with nanotechnology. As a result, some academics have called for stricter application of the , with delayed marketing approval, enhanced labelling and additional safety data development requirements in relation to certain forms of nanotechnology.
The Royal Society report identified a risk of nanoparticles or nanotubes being released during disposal, destruction and recycling, and recommended that "manufacturers of products that fall under extended producer responsibility regimes such as end-of-life regulations publish procedures outlining how these materials will be managed to minimize possible human and environmental exposure" (p. xiii).
The Center for Nanotechnology in Society has found that people respond to nanotechnologies differently, depending on application – with participants in
more positive about nanotechnologies for energy than health applications – suggesting that any public calls for nano regulations may differ by technology sector.
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Drexler, K. Eric (1986). Engines of Creation: The Coming Era of Nanotechnology. Doubleday.  .
Drexler, K. Eric (1992). Nanosystems: Molecular Machinery, Manufacturing, and Computation. New York: John Wiley & Sons.  .
, , 17 April 2012.
Saini, R Saini, S Sharma, Sugandha (2010). . Journal of Cutaneous and Aesthetic Surgery. 3 (1): 32–33. :.  .  .
Buzea, C.; Pacheco, I. I.; Robbie, K. (2007). "Nanomaterials and nanoparticles: Sources and toxicity". Biointerphases. 2 (4): MR17–MR71. :.  .
Binnig, G.; Rohrer, H. (1986). "Scanning tunneling microscopy". IBM Journal of Research and Development. 30 (4): 355–69.
. Nobelprize.org. 15 October .
Kroto, H. W.; Heath, J. R.; O'Brien, S. C.; Curl, R. F.; Smalley, R. E. (1985). "C60: Buckminsterfullerene". Nature. 318 (6042): 162–163. :. :.
Adams, W. W.; Baughman, R. H. (2005). "RETROSPECTIVE: Richard E. Smalley ()". Science. 310 (5756): 1916. :.  .
. Royal Society and Royal Academy of Engineering. July .
. Chemical & Engineering News. American Chemical Society. 81 (48): 37–42. 1 December 2003. : 2010.
. The Project on Emerging Nanotechnologies. .
Allhoff, F Lin, P Moore, Daniel (2010). What is nanotechnology and why does it matter?: from science to ethics. John Wiley and Sons. pp. 3–5.  .
Prasad, S. K. (2008). Modern Concepts in Nanotechnology. Discovery Publishing House. pp. 31–32.  .
Kahn, Jennifer (2006). "Nanotechnology". National Geographic. 2006 (June): 98–119.
Kralj, S Makovec, Darko (27 October 2015). "Magnetic Assembly of Superparamagnetic Iron Oxide Nanoparticle Clusters into Nanochains and Nanobundles". ACS Nano. 9 (10): . :.
Rodgers, P. (2006). "Nanoelectronics: Single file". Nature Nanotechnology. :.
Lubick N; Betts, Kellyn (2008). "Silver socks have cloudy lining". Environ Sci Technol. 42 (11): 3910. :. :.  .
Phoenix, Chris (March 2005) . crnano.org
. imm.org.
California NanoSystems Institute
. Chemical and Engineering News. 81 (48): 37–42. December 1, 2003.
Regan, BC; Aloni, S; Jensen, K; Ritchie, RO; Zettl, A (2005).
(PDF). Nano letters. 5 (9): 1730–3. :. :.  .
Regan, B. C.; Aloni, S.; Jensen, K.; Zettl, A. (2005).
(PDF). Applied Physics Letters. 86 (12): 123119. :. :.
Goodman, R.P.; Schaap, I.A.T.; Tardin, C.F.; Erben, C.M.; Berry, R.M.; Schmidt, C.F.; Turberfield, A.J. (9 December 2005). "Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication". . 310 (5754): . :. :.  .  .
Narayan, R. J.; Kumta, P. N.; Sfeir, Ch.; Lee, D-H; Choi, D.; Olton, D. (2004). "Nanostructured Ceramics in Medical Devices: Applications and Prospects". JOM. 56 (10): 38–43. :. :.
Cho, H Pinkhassik, E David, V Stuart, J Hasty, Karen (31 May 2015). . Nanomedicine: Nanotechnology, Biology and Medicine. Elsevier. 11 (4): 939–946. : 2015.
Kerativitayanan, P Carrow, James K.; Gaharwar, Akhilesh K. (May 2015). "Nanomaterials for Engineering Stem Cell Responses". Advanced Healthcare Materials. 4: 1600–27. :.  .
Gaharwar, A.K. [et al., edited by] (2013). Nanomaterials in tissue engineering : fabrication and applications. Oxford: Woodhead Publishing.  .
Gaharwar, AK; Peppas, NA; Khademhosseini, A (March 2014). . Biotechnology and Bioengineering. 111 (3): 441–53. :.  .  .
Levins, Christopher G.; Schafmeister, Christian E. (2006). "The Synthesis of Curved and Linear Structures from a Minimal Set of Monomers". ChemInform. 37 (5). :.
. National Nanotechnology Initiative. Archived from
. Nobelprize.org.
Das S, Gates AJ, Abdu HA, Rose GS, Picconatto CA, Ellenbogen JC (2007). "Designs for Ultra-Tiny, Special-Purpose Nanoelectronic Circuits". IEEE Transactions on Circuits and Systems I. 54 (11): . :.
Mashaghi, S.; Jadidi, T.; Koenderink, G.; Mashaghi, A. . Int. J. Mol. Sci. 2013 (14): .
Hogan, C. Michael (2010)
in Encyclopedia of Earth. National Council for Science and the Environment. eds. S. Draggan and C. Cleveland
Ghalanbor Z, Marashi SA, Ranjbar B (2005). "Nanotechnology helps medicine: nanoscale swimmers and their future applications". Med Hypotheses. 65 (1): 198–199. :.  .
Kubik T, Bogunia-Kubik K, Sugisaka M (2005). "Nanotechnology on duty in medical applications". Curr Pharm Biotechnol. 6 (1): 17–33.  .
Leary, SP; Liu, CY; Apuzzo, ML (2006). "Toward the Emergence of Nanoneurosurgery: Part III-Nanomedicine: Targeted Nanotherapy, Nanosurgery, and Progress Toward the Realization of Nanoneurosurgery". Neurosurgery. 58 (6): . :.  .
Shetty RC (2005). "Potential pitfalls of nanotechnology in its applications to medicine: immune incompatibility of nanodevices". Med Hypotheses. 65 (5): 998–9. :.  .
Cavalcanti, A.; Shirinzadeh, B.; Freitas, R.; Kretly, L. (2007). "Medical Nanorobot Architecture Based on Nanobioelectronics". Recent Patents on Nanotechnology. 1: 1–10. :.  .
Boukallel M, Gauthier M, Dauge M, Piat E, Abadie J (2007). "Smart microrobots for mechanical cell characterization and cell convoying". IEEE Trans. Biomed. Eng. 54 (8): 1536–40. :.  .
Lapshin, R. V. (2004).
(PDF). Nanotechnology. UK: IOP. 15 (9): . :. :.  .
Lapshin, R. V. (2011). "Feature-oriented scanning probe microscopy". In H. S. Nalwa.
(PDF). 14. USA: American Scientific Publishers. pp. 105–115.  .
Kafshgari, MH; Voelcker, NH; Harding, FJ (2015). "Applications of zero-valent silicon nanostructures in biomedicine". Nanomedicine (Lond). 10 (16): 2553–71. :.  .
Rajan, R Jose, S Mukund, V. P. B Vasudevan, Deepa T. (). . Journal of Advanced Pharmaceutical Technology & Research. 2 (3): 138–143. :.  .  .  .
Kurtoglu M. E.; Longenbach T.; Reddington P.; Gogotsi Y. (2011). "Effect of Calcination Temperature and Environment on Photocatalytic and Mechanical Properties of Ultrathin Sol–Gel Titanium Dioxide Films". Journal of the American Ceramic Society. 94 (4): . :.
. nnin.org. .
at NanoandMe.org
at NanoandMe.org
at NanoandMe.org
at Wikipedia.org
. . September 2014
Cassidy (2014). "Nanotechnology in the Regeneration of Complex Tissues". Bone and Tissue Regeneration Insights: 25. :.
Cassidy, J. W.; Roberts, J. N.; Smith, C. A.; Robertson, M.; White, K.; Biggs, M. J.; Oreffo, R. O. C.; Dalby, M. J. (2014). "Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces: The role of focal adhesion maturation". Acta Biomaterialia. 10 (2): 651–660. :.
Amir, Y.; Ben-Ishay, E.; Levner, D.; Ittah, S.; Abu-Horowitz, A.; Bachelet, I. (2014). "Universal computing by DNA origami robots in a living animal". Nature Nanotechnology. 9 (5): 353–357. :. :.
. National Institute for Occupational Safety and Health. June 15, 2012.
. National Institute for Occupational Safety and Health. November 7, 2012.
Lubick, N; Betts, Kellyn (2008). "Silver socks have cloudy lining". Environmental Science & Technology. 42 (11): 3910. :. :.  .
Murray R.G.E. (1993) Advances in Bacterial Paracrystalline Surface Layers. T. J. Beveridge, S. F. Koval (Eds.). Plenum Press. . pp. 3–9.
Harthorn, Barbara Herr (January 23, 2009) . Nanotechnology Today.
Project on Emerging Nanotechnologies. Retrieved on .
DelVecchio, Rick (November 24, 2006) .
Bray, Hiawatha (January 26, 2007) .
. . July 2008.
Encyclopedia of Nanoscience and Society, edited by David H. Guston, Sage Publications, 2010; see Articles on Insurance and Reinsurance (by I. Lippert).
Byrne, J. D.; Baugh, J. A. (2008). . McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students. 11 (1): 43–50.  .  .
Elder, A. (2006).
urmc.rochester.edu
September 21, 2006, at the .
Wu, J; Liu, W; Xue, C; Zhou, S; Lan, F; Bi, L; Xu, H; Yang, X; Zeng, FD (2009). "Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure". . 191 (1): 1–8. :.  .
Jonaitis, TS; Card, JW; Magnuson, B (2010). "Concerns regarding nano-sized titanium dioxide dermal penetration and toxicity study". Toxicology letters. 192 (2): 268–9. :.  .
Schneider, Andrew (March 24, 2010) . AOL News
Weiss, R. (2008).
Paull, J. & Lyons, K. (2008).
(PDF). Journal of Organic Systems. 3: 3–22.
Smith, Rebecca (August 19, 2009). . London: Telegraph 2010.
Schinwald, A.; Murphy, F. A.; Prina-Mello, A.; Poland, C. A.; Byrne, F.; Movia, D.; Glass, J. R.; Dickerson, J. C.; Schultz, D. A.; Jeffree, C. E.; MacNee, W.; Donaldson, K. (2012). "The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma". Toxicological Sciences. 128 (2): 461–470. :.
Acientific American.
Kevin Rollins (Nems Mems Works, LLC). . Volume 6 – Issue 2 2010.
Bowman D, Hodge G (2006). "Nanotechnology: Mapping the Wild Regulatory Frontier". Futures. 38 (9): . :.
Davies, J. C. (2008). .
Rowe, G. (2005). "Difficulties in evaluating public engagement initiatives: Reflections on an evaluation of the UK GM Nation? Public debate about transgenic crops". Public Understanding of Science. 14 (4): 331–352. :.
Maynard, A.. (). Retrieved on .
May 29, 2008, at the .
Faunce, T.; Murray, K.; Nasu, H.; Bowman, D. (2008). "Sunscreen Safety: The Precautionary Principle, the Australian Therapeutic Goods Administration and Nanoparticles in Sunscreens". NanoEthics. 2 (3): 231–240. :.
Thomas F Katherine M Hitoshi Nasu & Diana Bowman (24 July 2008).
(PDF). Springer Science + Business Media B.V 2009.
Wikimedia Commons has media related to .
Wikibooks has a book on the topic of:
At , you can learn more and teach others about Nanotechnology at the
(A Vega/BBC/OU Video Discussion).
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&&查看话题
感觉Nanotechnology投稿怎么这么随意呢。。。
虽然之前看了很多的文章，说Nanotechnology的投稿比较随意，但是今天自己提交的时候，还是深深的被雷到了。
（1）也没有注册帐户，直接就提交了。
（2）只有1页的信息让我填，好少啊。以前APL要写好多页呢。
（3）最后一步是上传文件，也没有什么提示，上传完了之后，就直接一下子跳到Submission Complete。什么也没说，就完了。。。
（4）随后收到一封邮件，说收到了提交的手稿，然后给了临时的ID，说过几天再给永久的ID，到时候才能查状态。
&&总体来讲，有点不负责任的感觉。。。 不像是个正规的期刊啊。。。
&&请问大家，下面我就等着啦？也没什么事情啊？
&&还有，这个杂志不是说不让推荐人嘛，怎么好像有这个选项，我推荐了几个审稿人，希望能选上啊。。。
什么。2个月没有送审？ 怎么可能？
我还要抓紧时间毕业呢？ 怎么办啊。。。。
我原来是投了APL，被reject，老板非要投Nanotechnology，这个可怎么办啊？。。。。
发了两封催告信了，编辑都不理睬，准备撤稿，以后再也不投这个了
个人觉得这个杂志的编辑还是很负责的，给他们发邮件基本上一两天就能得到答复，态度也还不错。IOP的投稿系统还好吧，我倒是很喜欢这种简洁的投稿流程。
应该还不错吧，从IF上看，但是据说还是不如APL的说
请问in progress 是还在编辑手里吗，有木有送审啊~谢谢了，手里有篇文章就是这个状态~
我也和你一样，出现过同样的问题，快两周了，没有音讯。想请问下，你的文章后来是什么情况
研究生必备与500万研究生在线互动！
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随时随地聊科研From Wikipedia, the free encyclopedia
For the materials science journal, see .
Nanotechnology ("nanotech") is manipulation of matter on an , , and
scale. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as . A more generalized description of nanotechnology was subsequently established by the , which defines nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 . This definition reflects the fact that
effects are important at this
scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore common to see the plural form "nanotechnologies" as well as "nanoscale technologies" to refer to the broad range of research and applications whose common trait is size. Because of the variety of potential applications (including industrial and military), governments have invested billions of dollars in nanotechnology research. Until 2012, through its National Nanotechnology Initiative, the USA has invested 3.7 billion dollars, the European Union has invested 1.2 billion and Japan 750 million dollars.
Nanotechnology as defined by size is naturally very broad, including fields of science as diverse as , , , , , , etc. The associated research and applications are equally diverse, ranging from extensions of conventional
to completely new approaches based upon , from developing
with dimensions on the nanoscale to .
Scientists currently debate the future . Nanotechnology may be able to create many new materials and devices with a vast range of , such as in , ,
energy production, and consumer products. On the other hand, nanotechnology raises many of the same issues as any new technology, including concerns about the
and environmental impact of nanomaterials, and their potential effects on global economics, as well as speculation about various . These concerns have led to a debate among advocacy groups and governments on whether special
is warranted.
Main article:
The concepts that seeded nanotechnology were first discussed in 1959 by renowned physicist
in his talk , in which he described the possibility of synthesis via direct manipulation of atoms. The term "nano-technology" was first used by
in 1974, though it was not widely known.
Comparison of Nanomaterials Sizes
Inspired by Feynman's concepts,
used the term "nanotechnology" in his 1986 book , which proposed the idea of a nanoscale "assembler" which would be able to build a copy of itself and of other items of arbitrary complexity with atomic control. Also in 1986, Drexler co-founded
(with which he is no longer affiliated) to help increase public awareness and understanding of nanotechnology concepts and implications.
Thus, emergence of nanotechnology as a field in the 1980s occurred through convergence of Drexler's theoretical and public work, which developed and popularized a conceptual framework for nanotechnology, and high-visibility experimental advances that drew additional wide-scale attention to the prospects of atomic control of matter. In the 1980s, two major breakthroughs sparked the growth of nanotechnology in modern era.
First, the invention of the
in 1981 which provided unprecedented visualization of individual atoms and bonds, and was successfully used to manipulate individual atoms in 1989. The microscope's developers
received a
in 1986. Binnig,
and Gerber also invented the analogous
that year.
Buckminsterfullerene C60, also known as the , is a representative member of the
known as . Members of the fullerene family are a major subject of research falling under the nanotechnology umbrella.
were discovered in 1985 by , , and , who together won the 1996 . C60 was not initially describ the term was used regarding subsequent work with related
tubes (called
and sometimes called Bucky tubes) which suggested potential applications for nanoscale electronics and devices.
In the early 2000s, the field garnered increased scientific, political, and commercial attention that led to both controversy and progress. Controversies emerged regarding the definitions and potential implications of nanotechnologies, exemplified by the 's report on nanotechnology. Challenges were raised regarding the feasibility of applications envisioned by advocates of molecular nanotechnology, which culminated in a public debate between Drexler and Smalley in 2001 and 2003.
Meanwhile, commercialization of products based on advancements in nanoscale technologies began emerging. These products are limited to bulk applications of
and do not involve atomic control of matter. Some examples include the
platform for using
as an antibacterial agent, -based transparent sunscreens,
strengthening using silica nanoparticles, and carbon nanotubes for stain-resistant textiles.
Governments moved to promote and
into nanotechnology, such as in the U.S. with the , which formalized a size-based definition of nanotechnology and established funding for research on the nanoscale, and in Europe via the European .
By the mid-2000s new and serious scientific attention began to flourish. Projects emerged to produce nanotechnology roadmaps which center on atomically precise manipulation of matter and discuss existing and projected capabilities, goals, and applications.
Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced. In its original sense, nanotechnology refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products.
(nm) is one billionth, or 10-9, of a meter. By comparison, typical carbon-carbon , or the spacing between these
in a , are in the range 0.12–0.15 nm, and a
double-helix has a diameter around 2 nm. On the other hand, the smallest
life-forms, the bacteria of the genus , are around 200 nm in length. By convention, nanotechnology is taken as the scale range 1 to 100 nm following the definition used by the National Nanotechnology Initiative in the US. The lower limit is set by the size of atoms (hydrogen has the smallest atoms, which are approximately a quarter of a nm diameter) since nanotechnology must build its devices from atoms and molecules. The upper limit is more or less arbitrary but is around the size below which phenomena not observed in larger structures start to become apparent and can be made use of in the nano device. These new phenomena make nanotechnology distinct from devices which are merely miniaturised versions of a such devices are on a larger scale and come under the description of .
To put that scale in another context, the comparative size of a nanometer to a meter is the same as that of a marble to the size of the earth. Or another way of putting it: a nanometer is the amount an average man's beard grows in the time it takes him to raise the razor to his face.
Two main approaches are used in nanotechnology. In the "bottom-up" approach, materials and devices are built from molecular components which
chemically by principles of . In the "top-down" approach, nano-objects are constructed from larger entities without atomic-level control.
Areas of physics such as , ,
have evolved during the last few decades to provide a basic scientific foundation of nanotechnology.
on a clean () surface, as visualized using . The positions of the individual atoms composing the surface are visible.
Main article:
Several phenomena become pronounced as the size of the system decreases. These include
effects, as well as
effects, for example the " size effect" where the electronic properties of solids are altered with great reductions in particle size. This effect does not come into play by going from macro to micro dimensions. However, quantum effects can become significant when the nanometer size range is reached, typically at distances of 100 nanometers or less, the so-called . Additionally, a number of physical (mechanical, electrical, optical, etc.) properties change when compared to macroscopic systems. One example is the increase in surface area to volume ratio altering mechanical, thermal and catalytic properties of materials. Diffusion and reactions at nanoscale, nanostructures materials and nanodevices with fast ion transport are generally referred to nanoionics. Mechanical properties of nanosystems are of interest in the nanomechanics research. The catalytic activity of nanomaterials also opens potential risks in their interaction with .
Materials reduced to the nanoscale can show different properties compared to what they exhibit on a macroscale, enabling unique applications. For instance, opaque substances can become transparent (copper); stable materials can turn combustible (aluminium); insoluble materials may become soluble (gold). A material such as gold, which is chemically inert at normal scales, can serve as a potent chemical
at nanoscales. Much of the fascination with nanotechnology stems from these quantum and surface phenomena that matter exhibits at the nanoscale.
Main article:
has reached the point where it is possible to prepare small molecules to almost any structure. These methods are used today to manufacture a wide variety of useful chemicals such as
or commercial . This ability raises the question of extending this kind of control to the next-larger level, seeking methods to assemble these single molecules into
consisting of many molecules arranged in a well defined manner.
These approaches utilize the concepts of molecular self-assembly and/or
to automatically arrange themselves into some useful conformation through a
approach. The concept of molecular recognition is especially important: molecules can be designed so that a specific configuration or arrangement is favored due to
. The Watson–Crick
rules are a direct result of this, as is the specificity of an
being targeted to a single , or the specific
itself. Thus, two or more components can be designed to be complementary and mutually attractive so that they make a more complex and useful whole.
Such bottom-up approaches should be capable of producing devices in parallel and be much cheaper than top-down methods, but could potentially be overwhelmed as the size and complexity of the desired assembly increases. Most useful structures require complex and thermodynamically unlikely arrangements of atoms. Nevertheless, there are many examples of self-assembly based on molecular recognition in , most notably Watson–Crick basepairing and enzyme-substrate interactions. The challenge for nanotechnology is whether these principles can be used to engineer new constructs in addition to natural ones.
Main article:
Molecular nanotechnology, sometimes called molecular manufacturing, describes engineered nanosystems (nanoscale machines) operating on the molecular scale. Molecular nanotechnology is especially associated with the , a machine that can produce a desired structure or device atom-by-atom using the principles of . Manufacturing in the context of
is not related to, and should be clearly distinguished from, the conventional technologies used to manufacture nanomaterials such as carbon nanotubes and nanoparticles.
When the term "nanotechnology" was independently coined and popularized by
(who at the time was unaware of an
by Norio Taniguchi) it referred to a future manufacturing technology based on
systems. The premise was that molecular scale biological analogies of traditional machine components demonstrated molecular machines were possible: by the countless examples found in biology, it is known that sophisticated,
can be produced.
It is hoped that developments in nanotechnology will make possible their construction by some other means, perhaps using
principles. However, Drexler and other researchers have proposed that advanced nanotechnology, although perhaps initially implemented by biomimetic means, ultimately could be based on mechanical engineering principles, namely, a manufacturing technology based on the mechanical functionality of these components (such as gears, bearings, motors, and structural members) that would enable programmable, positional assembly to atomic specification. The physics and engineering performance of exemplar designs were analyzed in Drexler's book Nanosystems.
In general it is very difficult to assemble devices on the atomic scale, as one has to position atoms on other atoms of comparable size and stickiness. Another view, put forth by Carlo Montemagno, is that future nanosystems will be hybrids of silicon technology and biological molecular machines. Richard Smalley argued that mechanosynthesis are impossible due to the difficulties in mechanically manipulating individual molecules.
This led to an exchange of letters in the
publication
in 2003. Though biology clearly demonstrates that molecular machine systems are possible, non-biological molecular machines are today only in their infancy. Leaders in research on non-biological molecular machines are Dr.
and his colleagues at Lawrence Berkeley Laboratories and UC Berkeley. They have constructed at least three distinct molecular devices whose motion is controlled from the desktop with changing voltage: a nanotube , a molecular actuator, and a nanoelectromechanical relaxation oscillator. See
for more examples.
An experiment indicating that positional molecular assembly is possible was performed by Ho and Lee at
in 1999. They used a scanning tunneling microscope to move an individual carbon monoxide molecule (CO) to an individual iron atom (Fe) sitting on a flat silver crystal, and chemically bound the CO to the Fe by applying a voltage.
Graphical representation of a , useful as a .
is an artificially
nanostructure of the type made in the field of . Each edge of the tetrahedron is a 20 base pair DNA , and each vertex is a three-arm junction.
Rotating view of C60, one kind of fullerene.
This device transfers energy from nano-thin layers of
above them, causing the nanocrystals to emit visible light.
The nanomaterials field includes subfields which develop or study materials having unique properties arising from their nanoscale dimensions.
has given rise to many materials which may be useful in nanotechnology, such as carbon nanotubes and other fullerenes, and various nanoparticles and . Nanomaterials with fast ion transport are related also to nanoionics and nanoelectronics.
Nanoscale materials can also be used f most present commercial applications of nanotechnology are of this flavor.
Progress has been made in using these materials for
Nanoscale materials such as
are sometimes used in
which combats the cost of traditional
solar cells.
Development of applications incorporating semiconductor
to be used in the next generation of products, such as display technology, lighting, solar cells an see .
Recent application of
include a range of
applications, such as , , and .
These seek to arrange smaller components into more complex assemblies.
DNA nanotechnology utilizes the specificity of Watson–Crick basepairing to construct well-defined structures out of DNA and other .
Approaches from the field of "classical" chemical synthesis (Inorganic and ) also aim at designing molecules with well-defined shape (e.g. ).
More generally, molecular self-assembly seeks to use concepts of supramolecular chemistry, and molecular recognition in particular, to cause single-molecule components to automatically arrange themselves into some useful conformation.
tips can be used as a nanoscale "write head" to deposit a chemical upon a surface in a desired pattern in a process called . This technique fits into the larger subfield of .
These seek to create smaller devices by using larger ones to direct their assembly.
Many technologies that descended from conventional
for fabricating
are now capable of creating features smaller than 100 nm, falling under the definition of nanotechnology. -based hard drives already on the market fit this description, as do
(ALD) techniques.
received the Nobel Prize in Physics in 2007 for their discovery of Giant magnetoresistance and contributions to the field of spintronics.
Solid-state techniques can also be used to create devices known as
or NEMS, which are related to
can directly remove material, or even deposit material when suitable precursor gasses are applied at the same time. For example, this technique is used routinely to create sub-100 nm sections of material for analysis in .
Atomic force microscope tips can be used as a nanoscale "write head" to deposit a resist, which is then followed by an etching process to remove material in a top-down method.
These seek to develop components of a desired functionality without regard to how they might be assembled.
for the synthesis of anisotropic superparamagnetic materials such as recently presented .
seeks to develop molecules with useful electronic properties. These could then be used as single-molecule components in a nanoelectronic device. For an example see rotaxane.
Synthetic chemical methods can also be used to create , such as in a so-called .
seeks to apply biological methods and systems found in nature, to the study and design of engineering systems and modern technology.
is one example of the systems studied.
is the use of
for applications in nanotechnology, including use of viruses and lipid assemblies.
is a potential bulk-scale application.
These subfields seek to
what inventions nanotechnology might yield, or attempt to propose an agenda along which inquiry might progress. These often take a big-picture view of nanotechnology, with more emphasis on its societal implications than the details of how such inventions could actually be created.
Molecular nanotechnology is a proposed approach which involves manipulating single molecules in finely controlled, deterministic ways. This is more theoretical than the other subfields, and many of its proposed techniques are beyond current capabilities.
centers on self-sufficient machines of some functionality operating at the nanoscale. There are hopes for applying nanorobots in medicine, but it may not be easy to do such a thing because of several drawbacks of such devices. Nevertheless, progress on innovative materials and methodologies has been demonstrated with some patents granted about new nanomanufacturing devices for future commercial applications, which also progressively helps in the development towards nanorobots with the use of embedded nanobioelectronics concepts.
Productive nanosystems are "systems of nanosystems" which will be complex nanosystems that produce atomically precise parts for other nanosystems, not necessarily using novel nanoscale-emergent properties, but well-understood fundamentals of manufacturing. Because of the discrete (i.e. atomic) nature of matter and the possibility of exponential growth, this stage is seen as the basis of another industrial revolution. , one of the architects of the USA's National Nanotechnology Initiative, has proposed four states of nanotechnology that seem to parallel the technical progress of the Industrial Revolution, progressing from passive nanostructures to active nanodevices to complex
and ultimately to productive nanosystems.
seeks to design materials whose properties can be easily, reversibly and externally controlled though a fusion of
Due to the popularity and media exposure of the term nanotechnology, the words
have been coined in analogy to it, although these are only used rarely and informally.
Nanomaterials can be classified in 0D, 1D, 2D and 3D . The dimensionality play a major role in determining the characteristic of nanomaterials including ,
characteristics. With the decrease in dimensionality, an increase in surface-to-volume ratio is observed. This indicate that smaller dimensional
have higher surface area compared to 3D nanomaterials. Recently,
are extensively investigated for , ,
applications.
setup. A microfabricated
with a sharp tip is deflected by features on a sample surface, much like in a
but on a much smaller scale. A
beam reflects off the backside of the cantilever into a set of , allowing the deflection to be measured and assembled into an image of the surface.
There are several important modern developments. The
(AFM) and the
(STM) are two early versions of scanning probes that launched nanotechnology. There are other types of . Although conceptually similar to the scanning
developed by
in 1961 and the
(SAM) developed by
and coworkers in the 1970s, newer scanning probe microscopes have much higher resolution, since they are not limited by the wavelength of sound or light.
The tip of a scanning probe can also be used to manipulate nanostructures (a process called positional assembly).
methodology may be a promising way to implement these nanomanipulations in automatic mode. However, this is still a slow process because of low scanning velocity of the microscope.
Various techniques of nanolithography such as ,
dip pen nanolithography,
were also developed. Lithography is a top-down fabrication technique where a bulk material is reduced in size to nanoscale pattern.
Another group of nanotechnological techniques include those used for fabrication of
and , those used in semiconductor fabrication such as deep ultraviolet lithography, electron beam lithography, focused ion beam machining, nanoimprint lithography, atomic layer deposition, and molecular vapor deposition, and further including molecular self-assembly techniques such as those employing di-block copolymers. The precursors of these techniques preceded the nanotech era, and are extensions in the development of scientific advancements rather than techniques which were devised with the sole purpose of creating nanotechnology and which were results of nanotechnology research.
The top-down approach anticipates nanodevices that must be built piece by piece in stages, much as manufactured items are made. Scanning probe microscopy is an important technique both for characterization and synthesis of nanomaterials. Atomic force microscopes and scanning tunneling microscopes can be used to look at surfaces and to move atoms around. By designing different tips for these microscopes, they can be used for carving out structures on surfaces and to help guide self-assembling structures. By using, for example, feature-oriented scanning approach, atoms or molecules can be moved around on a surface with scanning probe microscopy techniques. At present, it is expensive and time-consuming for mass production but very suitable for laboratory experimentation.
In contrast, bottom-up techniques build or grow larger structures atom by atom or molecule by molecule. These techniques include chemical synthesis,
and positional assembly.
is one tool suitable for characterisation of self assembled thin films. Another variation of the bottom-up approach is
or MBE. Researchers at
like John R. Arthur. Alfred Y. Cho, and Art C. Gossard developed and implemented MBE as a research tool in the late 1960s and 1970s. Samples made by MBE were key to the discovery of the fractional quantum Hall effect for which the 1998 Nobel Prize in Physics was awarded. MBE allows scientists to lay down atomically precise layers of atoms and, in the process, build up complex structures. Important for research on semiconductors, MBE is also widely used to make samples and devices for the newly emerging field of .
However, new therapeutic products, based on responsive nanomaterials, such as the ultradeformable, stress-sensitive
vesicles, are under development and already approved for human use in some countries.
One of the major applications of nanotechnology is in the area of
with 's being made of small
~10 nm in length. Here is a simulation of such a nanowire.
Nanostructures provide this surface with , which lets
roll down the .
Main article:
As of August 21, 2008, the
estimates that over 800 manufacturer-identified nanotech products are publicly available, with new ones hitting the market at a pace of 3–4 per week. The project lists all of the products in a publicly accessible online database. Most applications are limited to the use of "first generation" passive nanomaterials which includes titanium dioxide in sunscreen, cosmetics, surface coatings, an Carbon allotro silver in food packaging, clothing, disinfectants and
zinc oxide in sunscreens and cosmetics, surface coatings, paints and outdoor and cerium oxide as a fuel catalyst.
Further applications allow
to last longer,
to fly straighter, and even
to become more durable and have a harder surface.
have been infused with nanotechnology so that they will last longer and keep people cool in the summer.
are being infused with silver nanoparticles to heal cuts faster.
may become cheaper, faster, and contain more memory thanks to nanotechnology. Nanotechnology may have the ability to make existing medical applications cheaper and easier to use in places like the 's office and at home. Cars are being manufactured with
so they may need fewer
to operate in the future.
Scientists are now turning to nanotechnology in an attempt to develop diesel engines with cleaner exhaust fumes. Platinum is currently used as the diesel engine
in these engines. The catalyst is what cleans the exhaust fume particles. First a reduction catalyst is employed to take nitrogen atoms from NOx molecules in order to free oxygen. Next the oxidation catalyst oxidizes the hydrocarbons and carbon monoxide to form carbon dioxide and water. Platinum is used in both the reduction and the oxidation catalysts. Using platinum though, is inefficient in that it is expensive and unsustainable. Danish company InnovationsFonden invested DKK 15 million in a search for new catalyst substitutes using nanotechnology. The goal of the project, launched in the autumn of 2014, is to maximize surface area and minimize the amount of material required. Objects tend to minimize
two drops of water, for example, will join to form one drop and decrease surface area. If the catalyst's surface area that is exposed to the exhaust fumes is maximized, efficiency of the catalyst is maximized. The team working on this project aims to create nanoparticles that will not merge. Every time the surface is optimized, material is saved. Thus, creating these nanoparticles will increase the effectiveness of the resulting diesel engine catalyst—in turn leading to cleaner exhaust fumes—and will decrease cost. If successful, the team hopes to reduce platinum use by 25%.
Nanotechnology also has a prominent role in the fast developing field of . When designing scaffolds, researchers attempt to the mimic the nanoscale features of a 's microenvironment to direct its differentiation down a suitable lineage. For example, when creating scaffolds to support the growth of bone, researchers may mimic
Researchers have successfully used -based nanobots capable of carrying out logic functions to achieve targeted drug delivery in cockroaches. It is said that the computational power of these nanobots can be scaled up to that of a .
Main article:
An area of concern is the effect that industrial-scale manufacturing and use of nanomaterials would have on human health and the environment, as suggested by
research. For these reasons, some groups advocate that nanotechnology be regulated by governments. Others counter that overregulation would stifle scientific research and the development of beneficial innovations.
research agencies, such as the
are actively conducting research on potential health effects stemming from exposures to nanoparticles.
Some nanoparticle products may have . Researchers have discovered that
silver nanoparticles used in socks to reduce foot odor are being released in the wash. These particles are then flushed into the waste water stream and may destroy bacteria which are critical components of natural ecosystems, farms, and waste treatment processes.
Public deliberations on
in the US and UK carried out by the Center for Nanotechnology in Society found that participants were more positive about nanotechnologies for energy applications than for health applications, with health applications raising moral and ethical dilemmas such as cost and availability.
Experts, including director of the Woodrow Wilson Center's Project on Emerging Nanotechnologies David Rejeski, have testified that successful commercialization depends on adequate oversight, risk research strategy, and public engagement.
is currently the only city in the United States to reg
in 2008 considered enacting a similar law, but ultimately rejected it. Relevant for both research on and application of nanotechnologies, the
of nanotechnology is contested. Without state , the availability of private insurance for potential damages is seen as necessary to ensure that burdens are not socialised implicitly.
A video on the health and safety implications of nanotechnology
Main articles:
Nanofibers are used in several areas and in different products, in everything from aircraft wings to tennis rackets. Inhaling airborne nanoparticles and nanofibers may lead to a number of , e.g. . Researchers have found that when rats breathed in nanoparticles, the particles settled in the brain and lungs, which led to significant increases in biomarkers for inflammation and stress response and that nanoparticles induce skin aging through oxidative stress in hairless mice.
A two-year study at UCLA's School of Public Health found lab mice consuming nano-titanium dioxide showed DNA and chromosome damage to a degree "linked to all the big killers of man, namely cancer, heart disease, neurological disease and aging".
A major study published more recently in
suggests some forms of carbon nanotubes – a poster child for the "nanotechnology revolution" – could be as harmful as
if inhaled in sufficient quantities.
of the Institute of Occupational Medicine in Edinburgh, Scotland, who contributed to the article on
said "We know that some of them probably have the potential to cause mesothelioma. So those sorts of materials need to be handled very carefully." In the absence of specific regulation forthcoming from governments, Paull and Lyons (2008) have called for an exclusion of engineered nanoparticles in food. A newspaper article reports that workers in a paint factory developed serious lung disease and nanoparticles were found in their lungs.
Main article:
Calls for tighter regulation of nanotechnology have occurred alongside a growing debate related to the human health and safety risks of nanotechnology. There is significant debate about who is responsible for the regulation of nanotechnology. Some regulatory agencies currently cover some nanotechnology products and processes (to varying degrees) – by "bolting on" nanotechnology to existing regulations – there are clear gaps in these regimes. Davies (2008) has proposed a regulatory road map describing steps to deal with these shortcomings.
Stakeholders concerned by the lack of a regulatory framework to assess and control risks associated with the release of nanoparticles and nanotubes have drawn parallels with
("mad cow" disease), , genetically modified food, nuclear energy, reproductive technologies, biotechnology, and . Dr. Andrew Maynard, chief science advisor to the Woodrow Wilson Center's Project on Emerging Nanotechnologies, concludes that there is insufficient funding for human health and safety research, and as a result there is currently limited understanding of the human health and safety risks associated with nanotechnology. As a result, some academics have called for stricter application of the , with delayed marketing approval, enhanced labelling and additional safety data development requirements in relation to certain forms of nanotechnology.
The Royal Society report identified a risk of nanoparticles or nanotubes being released during disposal, destruction and recycling, and recommended that "manufacturers of products that fall under extended producer responsibility regimes such as end-of-life regulations publish procedures outlining how these materials will be managed to minimize possible human and environmental exposure" (p. xiii).
The Center for Nanotechnology in Society has found that people respond to nanotechnologies differently, depending on application – with participants in
more positive about nanotechnologies for energy than health applications – suggesting that any public calls for nano regulations may differ by technology sector.
Main article:
Drexler, K. Eric (1986). Engines of Creation: The Coming Era of Nanotechnology. Doubleday.  .
Drexler, K. Eric (1992). Nanosystems: Molecular Machinery, Manufacturing, and Computation. New York: John Wiley & Sons.  .
, , 17 April 2012.
Saini, R Saini, S Sharma, Sugandha (2010). . Journal of Cutaneous and Aesthetic Surgery. 3 (1): 32–33. :.  .  .
Buzea, C.; Pacheco, I. I.; Robbie, K. (2007). "Nanomaterials and nanoparticles: Sources and toxicity". Biointerphases. 2 (4): MR17–MR71. :.  .
Binnig, G.; Rohrer, H. (1986). "Scanning tunneling microscopy". IBM Journal of Research and Development. 30 (4): 355–69.
. Nobelprize.org. 15 October .
Kroto, H. W.; Heath, J. R.; O'Brien, S. C.; Curl, R. F.; Smalley, R. E. (1985). "C60: Buckminsterfullerene". Nature. 318 (6042): 162–163. :. :.
Adams, W. W.; Baughman, R. H. (2005). "RETROSPECTIVE: Richard E. Smalley ()". Science. 310 (5756): 1916. :.  .
. Royal Society and Royal Academy of Engineering. July .
. Chemical & Engineering News. American Chemical Society. 81 (48): 37–42. 1 December 2003. : 2010.
. The Project on Emerging Nanotechnologies. .
Allhoff, F Lin, P Moore, Daniel (2010). What is nanotechnology and why does it matter?: from science to ethics. John Wiley and Sons. pp. 3–5.  .
Prasad, S. K. (2008). Modern Concepts in Nanotechnology. Discovery Publishing House. pp. 31–32.  .
Kahn, Jennifer (2006). "Nanotechnology". National Geographic. 2006 (June): 98–119.
Kralj, S Makovec, Darko (27 October 2015). "Magnetic Assembly of Superparamagnetic Iron Oxide Nanoparticle Clusters into Nanochains and Nanobundles". ACS Nano. 9 (10): . :.
Rodgers, P. (2006). "Nanoelectronics: Single file". Nature Nanotechnology. :.
Lubick N; Betts, Kellyn (2008). "Silver socks have cloudy lining". Environ Sci Technol. 42 (11): 3910. :. :.  .
Phoenix, Chris (March 2005) . crnano.org
. imm.org.
California NanoSystems Institute
. Chemical and Engineering News. 81 (48): 37–42. December 1, 2003.
Regan, BC; Aloni, S; Jensen, K; Ritchie, RO; Zettl, A (2005).
(PDF). Nano letters. 5 (9): 1730–3. :. :.  .
Regan, B. C.; Aloni, S.; Jensen, K.; Zettl, A. (2005).
(PDF). Applied Physics Letters. 86 (12): 123119. :. :.
Goodman, R.P.; Schaap, I.A.T.; Tardin, C.F.; Erben, C.M.; Berry, R.M.; Schmidt, C.F.; Turberfield, A.J. (9 December 2005). "Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication". . 310 (5754): . :. :.  .  .
Narayan, R. J.; Kumta, P. N.; Sfeir, Ch.; Lee, D-H; Choi, D.; Olton, D. (2004). "Nanostructured Ceramics in Medical Devices: Applications and Prospects". JOM. 56 (10): 38–43. :. :.
Cho, H Pinkhassik, E David, V Stuart, J Hasty, Karen (31 May 2015). . Nanomedicine: Nanotechnology, Biology and Medicine. Elsevier. 11 (4): 939–946. : 2015.
Kerativitayanan, P Carrow, James K.; Gaharwar, Akhilesh K. (May 2015). "Nanomaterials for Engineering Stem Cell Responses". Advanced Healthcare Materials. 4: 1600–27. :.  .
Gaharwar, A.K. [et al., edited by] (2013). Nanomaterials in tissue engineering : fabrication and applications. Oxford: Woodhead Publishing.  .
Gaharwar, AK; Peppas, NA; Khademhosseini, A (March 2014). . Biotechnology and Bioengineering. 111 (3): 441–53. :.  .  .
Levins, Christopher G.; Schafmeister, Christian E. (2006). "The Synthesis of Curved and Linear Structures from a Minimal Set of Monomers". ChemInform. 37 (5). :.
. National Nanotechnology Initiative. Archived from
. Nobelprize.org.
Das S, Gates AJ, Abdu HA, Rose GS, Picconatto CA, Ellenbogen JC (2007). "Designs for Ultra-Tiny, Special-Purpose Nanoelectronic Circuits". IEEE Transactions on Circuits and Systems I. 54 (11): . :.
Mashaghi, S.; Jadidi, T.; Koenderink, G.; Mashaghi, A. . Int. J. Mol. Sci. 2013 (14): .
Hogan, C. Michael (2010)
in Encyclopedia of Earth. National Council for Science and the Environment. eds. S. Draggan and C. Cleveland
Ghalanbor Z, Marashi SA, Ranjbar B (2005). "Nanotechnology helps medicine: nanoscale swimmers and their future applications". Med Hypotheses. 65 (1): 198–199. :.  .
Kubik T, Bogunia-Kubik K, Sugisaka M (2005). "Nanotechnology on duty in medical applications". Curr Pharm Biotechnol. 6 (1): 17–33.  .
Leary, SP; Liu, CY; Apuzzo, ML (2006). "Toward the Emergence of Nanoneurosurgery: Part III-Nanomedicine: Targeted Nanotherapy, Nanosurgery, and Progress Toward the Realization of Nanoneurosurgery". Neurosurgery. 58 (6): . :.  .
Shetty RC (2005). "Potential pitfalls of nanotechnology in its applications to medicine: immune incompatibility of nanodevices". Med Hypotheses. 65 (5): 998–9. :.  .
Cavalcanti, A.; Shirinzadeh, B.; Freitas, R.; Kretly, L. (2007). "Medical Nanorobot Architecture Based on Nanobioelectronics". Recent Patents on Nanotechnology. 1: 1–10. :.  .
Boukallel M, Gauthier M, Dauge M, Piat E, Abadie J (2007). "Smart microrobots for mechanical cell characterization and cell convoying". IEEE Trans. Biomed. Eng. 54 (8): 1536–40. :.  .
Lapshin, R. V. (2004).
(PDF). Nanotechnology. UK: IOP. 15 (9): . :. :.  .
Lapshin, R. V. (2011). "Feature-oriented scanning probe microscopy". In H. S. Nalwa.
(PDF). 14. USA: American Scientific Publishers. pp. 105–115.  .
Kafshgari, MH; Voelcker, NH; Harding, FJ (2015). "Applications of zero-valent silicon nanostructures in biomedicine". Nanomedicine (Lond). 10 (16): 2553–71. :.  .
Rajan, R Jose, S Mukund, V. P. B Vasudevan, Deepa T. (). . Journal of Advanced Pharmaceutical Technology & Research. 2 (3): 138–143. :.  .  .  .
Kurtoglu M. E.; Longenbach T.; Reddington P.; Gogotsi Y. (2011). "Effect of Calcination Temperature and Environment on Photocatalytic and Mechanical Properties of Ultrathin Sol–Gel Titanium Dioxide Films". Journal of the American Ceramic Society. 94 (4): . :.
. nnin.org. .
at NanoandMe.org
at NanoandMe.org
at NanoandMe.org
at Wikipedia.org
. . September 2014
Cassidy (2014). "Nanotechnology in the Regeneration of Complex Tissues". Bone and Tissue Regeneration Insights: 25. :.
Cassidy, J. W.; Roberts, J. N.; Smith, C. A.; Robertson, M.; White, K.; Biggs, M. J.; Oreffo, R. O. C.; Dalby, M. J. (2014). "Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces: The role of focal adhesion maturation". Acta Biomaterialia. 10 (2): 651–660. :.
Amir, Y.; Ben-Ishay, E.; Levner, D.; Ittah, S.; Abu-Horowitz, A.; Bachelet, I. (2014). "Universal computing by DNA origami robots in a living animal". Nature Nanotechnology. 9 (5): 353–357. :. :.
. National Institute for Occupational Safety and Health. June 15, 2012.
. National Institute for Occupational Safety and Health. November 7, 2012.
Lubick, N; Betts, Kellyn (2008). "Silver socks have cloudy lining". Environmental Science & Technology. 42 (11): 3910. :. :.  .
Murray R.G.E. (1993) Advances in Bacterial Paracrystalline Surface Layers. T. J. Beveridge, S. F. Koval (Eds.). Plenum Press. . pp. 3–9.
Harthorn, Barbara Herr (January 23, 2009) . Nanotechnology Today.
Project on Emerging Nanotechnologies. Retrieved on .
DelVecchio, Rick (November 24, 2006) .
Bray, Hiawatha (January 26, 2007) .
. . July 2008.
Encyclopedia of Nanoscience and Society, edited by David H. Guston, Sage Publications, 2010; see Articles on Insurance and Reinsurance (by I. Lippert).
Byrne, J. D.; Baugh, J. A. (2008). . McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students. 11 (1): 43–50.  .  .
Elder, A. (2006).
urmc.rochester.edu
September 21, 2006, at the .
Wu, J; Liu, W; Xue, C; Zhou, S; Lan, F; Bi, L; Xu, H; Yang, X; Zeng, FD (2009). "Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure". . 191 (1): 1–8. :.  .
Jonaitis, TS; Card, JW; Magnuson, B (2010). "Concerns regarding nano-sized titanium dioxide dermal penetration and toxicity study". Toxicology letters. 192 (2): 268–9. :.  .
Schneider, Andrew (March 24, 2010) . AOL News
Weiss, R. (2008).
Paull, J. & Lyons, K. (2008).
(PDF). Journal of Organic Systems. 3: 3–22.
Smith, Rebecca (August 19, 2009). . London: Telegraph 2010.
Schinwald, A.; Murphy, F. A.; Prina-Mello, A.; Poland, C. A.; Byrne, F.; Movia, D.; Glass, J. R.; Dickerson, J. C.; Schultz, D. A.; Jeffree, C. E.; MacNee, W.; Donaldson, K. (2012). "The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma". Toxicological Sciences. 128 (2): 461–470. :.
Acientific American.
Kevin Rollins (Nems Mems Works, LLC). . Volume 6 – Issue 2 2010.
Bowman D, Hodge G (2006). "Nanotechnology: Mapping the Wild Regulatory Frontier". Futures. 38 (9): . :.
Davies, J. C. (2008). .
Rowe, G. (2005). "Difficulties in evaluating public engagement initiatives: Reflections on an evaluation of the UK GM Nation? Public debate about transgenic crops". Public Understanding of Science. 14 (4): 331–352. :.
Maynard, A.. (). Retrieved on .
May 29, 2008, at the .
Faunce, T.; Murray, K.; Nasu, H.; Bowman, D. (2008). "Sunscreen Safety: The Precautionary Principle, the Australian Therapeutic Goods Administration and Nanoparticles in Sunscreens". NanoEthics. 2 (3): 231–240. :.
Thomas F Katherine M Hitoshi Nasu & Diana Bowman (24 July 2008).
(PDF). Springer Science + Business Media B.V 2009.
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